Innovative Nerve Repair Solution Unveiled by TISSIUM MedTech

TISSIUM Introduces Breakthrough Nerve Repair System

TISSIUM, a forward-thinking privately-owned medtech company that specializes in developing biomorphic programmable polymers for tissue reconstruction, recently shared encouraging clinical results about its COAPTIUM CONNECT System. This innovative, atraumatic sutureless solution for peripheral nerve repair was showcased at a significant congress, highlighting its immense potential.

The Challenge of Peripheral Nerve Injuries

Peripheral nerve injuries are a considerable issue, often leading to complications such as impaired nerve function and a decline in the quality of life. Although traditional microsurgical techniques involving sutures are generally effective, they come with challenges like inconsistent recovery rates and risks of further nerve damage. TISSIUM's groundbreaking COAPTIUM CONNECT System addresses these challenges by providing a sutureless approach that minimizes trauma to the nerves themselves, leading to better long-term outcomes.

Clinical Study Overview

A pivotal prospective single-arm study investigated the performance of the COAPTIUM CONNECT System in patients suffering from digital nerve injuries. The study enrolled 12 participants, with 10 completing the necessary one-year follow-up period. The results were notably positive, showcasing:

• 100% procedural success defined by effective atraumatic coaptation using the polymer-assisted device.
• All patients regained full flexion and extension of their injured digits.
• No pain was reported by any participant at the 12-month mark, demonstrating the system's efficacy in promoting pain-free recovery.
• No complications associated with the study device were reported throughout the complete follow-up duration.
• There were no occurrences of neuromas.

Expert Insights on the Results

TISSIUM extends its gratitude to the dedicated study investigators, including Professor Randy Bindra from a prominent Australian university hospital and Dr. Michael Wagels. Their relentless work in exploring new avenues for treating digital nerve injuries embodies the spirit of medical innovation.

Dr. Bindra shared his perspective on the findings, noting that the results surpassed his expectations, stating, “Every patient in this trial was pain-free and exhibited remarkable healing.” Furthermore, Dr. Wagels echoed the sentiment, highlighting the importance of removing sutures for optimal nerve regeneration, ultimately benefiting patients well into the future.

The Future of Nerve Repair Technology

The COAPTIUM CONNECT System is positioned as a revolutionary advancement in nerve surgery. By employing a unique biopolymer platform, the system merges a bioresorbable light-activated surgical polymer with a protective coaptation chamber. This innovative setup eliminates the traditional reliance on microsutures, streamlining the repair process and enhancing overall nerve health and function.

As TISSIUM continues to innovate within the realm of tissue reconstruction, the company remains committed to expanding the capabilities of the COAPTIUM platform to serve a broader range of nerve repair applications. This commitment represents not just technological progress, but a promise to improve patient outcomes.

Company Background

TISSIUM is a MedTech company based in Paris, France, and Cambridge, USA. The company dedicates itself to the research and development of products derived from its proprietary portfolio of biosynthetic, biomorphic, and programmable polymers, addressing unmet clinical needs like atraumatic tissue repair.

The company's product pipeline comprises seven offerings spanning three sectors, namely atraumatic sutureless nerve repair, hernia repair, and cardiovascular sealants. Each product is meticulously crafted to contribute significantly to the tissue reconstruction landscape. Furthermore, TISSIUM also develops complementary delivery and activation devices that optimize performance and ease of use for its products.

The foundation of TISSIUM's technology is built upon world-class research led by esteemed professors who co-founded the company, ensuring a robust intellectual property base.

Contact Information

For further inquiries, please reach out to Romain Attard, Chief Financial Officer:

rattard@tissium.com

Frequently Asked Questions

What is the COAPTIUM CONNECT System?

The COAPTIUM CONNECT System is an innovative atraumatic sutureless solution designed for peripheral nerve repair, developed by TISSIUM.

What were the key findings of the clinical study?

The study revealed a 100% procedural success rate, with all participating patients regaining full mobility and reporting no pain after a year.

Who were the investigators involved in the study?

The study was led by Professor Randy Bindra and Dr. Michael Wagels, who played pivotal roles in investigating the innovative system.

How does the TISSIUM technology stand out in nerve repair?

TISSIUM's technology eliminates the need for microsutures, which can lead to improved regeneration of nerve tissues and overall better outcomes for patients.

What are TISSIUM's future plans?

TISSIUM is committed to expanding its COAPTIUM platform for broader applications in nerve repair and continuing its innovation in tissue reconstruction.

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