Purple Biotech's Innovative Approach in Oncology Conference Session
Panel Discussion Highlights at Horizons in Oncology Conference
Purple Biotech Ltd. (NASDAQ/TASE: PPBT) is set to make a significant impact at the upcoming Canaccord Genuity Horizons in Oncology Virtual Conference. The event, scheduled for April 7, will feature a panel discussion led by the Company's CEO, Gil Efron, during a session titled “New Radiotherapy and Targeted Therapy Approaches.” This engaging discussion, which will run from 2:00 PM to 2:50 PM ET, aims to explore cutting-edge strategies in cancer treatment.
Who is Purple Biotech?
Founded with dedication to oncology, Purple Biotech is dedicated to developing first-in-class therapies designed to combat tumor immune evasion and overcome drug resistance. Their remarkable portfolio includes innovative candidates such as CM24, NT219, and CAPTN-3. These therapeutics embody the company’s commitment to addressing unmet medical needs in cancer therapies.
Understanding CM24
CM24, a humanized monoclonal antibody, plays a pivotal role by targeting CEACAM1, known for its role in promoting tumor immune evasion and survival through various mechanisms. The development of CM24 is particularly promising, having shown remarkable efficacy in clinical studies, including a Phase 2 clinical trial for pancreatic ductal adenocarcinoma (PDAC). This study combined CM24 with nivolumab, an anti-PD-1 checkpoint inhibitor, leading to significant improvements across all endpoints.
The Potential of NT219
Another promising agent in Purple Biotech’s pipeline is NT219, a dual inhibitor that targets IRS1/2 and STAT3. Recent research from a Phase 1 dose escalation study indicates that NT219 may yield significant anti-tumor activity, especially when combined with cetuximab for patients with recurrent or metastatic squamous cell carcinoma of the head and neck. The Company is now set to collaborate with the University of Colorado to further develop this therapeutic solution in a Phase 2 study.
Exploring CAPTN-3
CAPTN-3 is Purple Biotech's innovative preclinical platform of conditionally activated tri-specific antibodies. This unique approach is designed to enhance localized immune responses within the tumor microenvironment. By utilizing cleavable capping technology, CAPTN-3 aims to confine therapeutic effects specifically to tumor sites, potentially maximizing therapeutic windows for patients. Furthermore, the first tri-specific antibody under development, IM1240, targets the 5T4 antigen, prevalent in diverse solid tumors, which promises to improve treatment outcomes.
The Road Ahead for Purple Biotech
As Purple Biotech prepares for its participation in the Canaccord Genuity conference, the company remains focused on pushing their innovative therapies through the regulatory process to bring them to market. With a commitment to addressing the complexities of cancer treatment, Purple Biotech's strategies reflect a keen understanding of the landscape of oncology and the challenges patients face.
Frequently Asked Questions
What is the purpose of Purple Biotech's participation in the conference?
The conference will serve as a platform for Purple Biotech to showcase its innovative cancer therapies and engage with industry experts, discussing the latest advancements in oncology.
What are the key therapies developed by Purple Biotech?
Purple Biotech focuses on ground-breaking therapies, notably CM24, NT219, and CAPTN-3, each aiming to address aspects of tumor resistance and immune evasion.
How does CM24 function therapeutically?
CM24 is a monoclonal antibody that blocks CEACAM1, promoting immune response against tumors and showing efficacy in clinical trials for pancreatic cancer.
What potential does NT219 hold?
NT219 targets IRS1/2 and STAT3 and has demonstrated promising anti-tumor activity, particularly in combination therapies for head and neck cancers.
Where is Purple Biotech headquartered?
The corporate headquarters of Purple Biotech is located in Rehovot, Israel, emphasizing its commitment to research and development in oncology.
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