Interleukin-1 (IL-1) and interleukin-6 (IL-6) are
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Posted On: 12/09/2023 6:25:26 AM
Quote:
Interleukin-1 (IL-1) and interleukin-6 (IL-6) are pro-inflammatory cytokines , and interleukin-2 (IL-2) and interleukin-12 (IL-12) are essential for the activation and function of T cells and NK cells, respectively. Over 40 different interleukins exist in humans, each with a distinct role and specificity [3]. Cancer and autoimmune diseases can be brought on by dysregulation of interleukins.
From my preliminary work-in-progress leronlimab regulator list. I have not checked all IL chemokines as of yet.
Quote:
IL-1b (via caspase-1 downreg)[-], IL-1Ra [+], IL-2 [-], IL-4 (-), IL-5, IL-6 (via CCL5) [-], IL-8, IL-10 [-], IL-13 [-], IL-16 [-], IL-17a [-], IL-18 (via caspase-1 downreg)[-], IL-33, IL-36 (via TNF-a and ILF downreg)[-]
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