Cytokines: https://pubmed.ncbi.nlm.nih.gov/375670
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Cytokines bind to specific receptors on target cells to activate intracellular signaling pathways that control diverse cellular functions, such as proliferation, differentiation, migration, and death. They are essential for the growth, activation, and operation of immune cells and the control of immunological reactions to pathogens, cancer cells, and other dangers. Based on their structural and functional properties, cytokines can be roughly categorized into different families, such as the tumor necrosis factor (TNF) family, interleukins, interferons, and chemokines . Leukocytes produce interleukins, a class of cytokines that have essential functions in coordinating and communicating with immune cells.
Interleukin-1 (IL-1) and interleukin-6 (IL-6) are pro-inflammatory cytokines , and interleukin-2 (IL-2) and interleukin-12 (IL-12) are essential for the activation and function of T cells and NK cells, respectively. Over 40 different interleukins exist in humans, each with a distinct role and specificity [3]. Cancer and autoimmune diseases can be brought on by dysregulation of interleukins.
Interleukins are cytokine member that plays critical roles in immune cell communication and coordination [interleukin signaling or production.
LL is an immune modulator. Jay L
Deadly covid is a cytokine storm .