CXCL16 has many similarities to CCL5 in recruitmen
Post# of 148165
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Posted On: 12/15/2022 2:09:29 AM
CXCL16 has many similarities to CCL5 in recruitment of inflammatory factors. CXCL16 upregulation is controlled by inflammation itself. With CCR5 being the main driver behind inflammation leronlimab should lower CXCL16 expression like it does with CXCL-1. One of the downregulation pathways would be CCR5 lowered> TIMP3 lowered> ADAM10 and ADAM17 lowered> CXCL16 lowered.
So leronlimab could provide a similar benefit of any drug that specifically targets CXCL16.
So leronlimab could provide a similar benefit of any drug that specifically targets CXCL16.
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