Only problem with AAV transgene product (leronlima
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Posted On: 12/15/2022 2:16:23 AM
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Only problem with AAV transgene product (leronlimab) production waning is that you can't re-dose with AAV, as the body builds up immunity to it after the first dose.
In many AAVs that might be the case due to antibody formation. From Dr. Sacha's work we see a short span where antibodies develop then go away. That they go away may be because of leronlimab's ability to lower autoimmunity.
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