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Posted On: 08/07/2020 1:18:19 AM
Post# of 148936
"Dr. Patterson, from most recent YouTube with Dr. Yo when asked what level of statistical significance will FDA require, replied quite peevishly that results are statistically significant or not."
That's true for the FULL results, but wrong for the interim results... trial definitely won't be stopped at the interim point if p-value is 0.045 or 0.039 for instance, since it would instill doubt as to efficacy, because the full result could very easily lie above 0.05.
https://online.stat.psu.edu/stat509/node/80/
That's true for the FULL results, but wrong for the interim results... trial definitely won't be stopped at the interim point if p-value is 0.045 or 0.039 for instance, since it would instill doubt as to efficacy, because the full result could very easily lie above 0.05.
https://online.stat.psu.edu/stat509/node/80/
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