GoLiver Therapeutics Wins Major Funding for Innovative Liver Treatment
GoLiver Therapeutics Secures Major Funding for GLTX-001
GoLiver Therapeutics is thrilled to announce its recent victory in the France 2030 initiative, where it has secured an impressive €1.6 million in funding aimed at advancing its cutting-edge biomedicine, GLTX-001. This revolutionary project focuses on providing a novel treatment for severe liver failures using pluripotent stem cell technology.
Innovative Approach to Severe Liver Diseases
At the heart of GoLiver Therapeutics' mission is the ambition to address the growing crisis of liver diseases worldwide. With over 800 million individuals affected by chronic liver conditions, the company is on the forefront of developing a biomedicine that aims to alleviate the need for liver transplants, which are currently the sole curative option for patients with end-stage liver disease.
The GOCLINICALS Project
The GOCLINICALS project represents a significant step in proving the safety, efficacy, and tolerability of GLTX-001. This innovative treatment utilizes an injectable solution made from allogeneic liver cells, designed for rapid preparation at the patient’s bedside. Preclinical data shows that GLTX-001 significantly protects liver cells from destruction and enhances the organ’s natural regenerative abilities.
Industrial Bioproduction Capabilities
One of the standout features of GoLiver Therapeutics is its iMillenium™ manufacturing platform. This state-of-the-art facility overcomes the challenges typically associated with producing the billions of cells required for effective cell therapy. By leveraging advanced pluripotent stem cell technology, it achieves unparalleled yields and cost-effectiveness. The infrastructure also allows for swift deployment in the market, using bioreactors that are already established in contract manufacturing organizations (CDMOs).
Commitment to Healthcare Innovation
Tuan Huy Nguyen, President of GoLiver Therapeutics, expressed gratitude towards France 2030 for their support, emphasizing that this funding would propel the company towards developing its first advanced cell drug candidate. He remarked, “GLTX-001 will be groundbreaking for liver disease patients, with impressive preclinical results paving the way for routine clinical usage.”
Collaborative Efforts and Future Aspirations
To ensure the successful execution of GOCLINICALS, GoLiver Therapeutics will engage long-standing collaborations with notable partners, including the cell and gene therapy unit of Nantes University Hospital and the Paul-Brousse Hospital, one of France's leading liver transplant centers. This collaboration aims not only towards liver disease but also towards expanding the application of their cell-based therapies across various medical conditions, broadening their impact in the field of regenerative medicine.
Addressing a Global Health Challenge
Globally, liver failure claims over two million lives annually, and the number of available donor organs for transplantation is not sufficient to meet the demand. By harnessing patients' own liver cell regeneration, GoLiver Therapeutics aims to address this urgent medical need with high-quality bioproduced therapies.
About GoLiver Therapeutics
Founded in 2017 as a spin-off from Inserm and Nantes University, GoLiver Therapeutics is poised to become a leader in regenerative medicine, focusing on liver cell regeneration without the need for transplantation. The company has received numerous accolades, including recognition from the European Union and various national awards for its groundbreaking research in healthcare biotechnologies.
Frequently Asked Questions
What is GLTX-001?
GLTX-001 is a biomedicine developed by GoLiver Therapeutics, made from an injectable solution of frozen allogeneic liver cells aimed at treating severe liver diseases.
How does the iMillenium™ platform benefit GoLiver Therapeutics?
The iMillenium™ platform offers efficient production capabilities, enabling the manufacturing of billions of liver cells with high yield and cost-effectiveness, thus facilitating rapid clinical trials.
What is the GOCLINICALS project?
The GOCLINICALS project is an initiative to clinically test and validate the safety and efficacy of GLTX-001 in patients suffering from severe liver failure.
Who are GoLiver Therapeutics’ key partners?
Key partnerships include collaborations with the cell and gene therapy unit at Nantes University Hospital and the Paul-Brousse Hospital, both of which enhance research and clinical development.
What are the future aspirations of GoLiver Therapeutics?
GoLiver Therapeutics aims to diversify its therapeutic portfolio and expand its innovations in regenerative medicine beyond liver diseases, addressing various medical challenges.
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