Cuprina’s Innovative Research on Bullfrog-Derived Collagen Peptides

Exploring New Frontiers in Biotechnology
Cuprina Holdings (Cayman) Limited (NASDAQ: CUPR) is making waves in the biomedical and biotechnology sectors with exciting new research collaborations. The company's commitment to developing innovative products for chronic wound management, infertility, and the beauty industry reflects its dedication to enhancing human health. Cuprina's recent progress in studies with three prestigious academic institutions marks a significant step forward.
Collaborations with Leading Institutes
Cuprina's journey began with a consultancy agreement with Republic Polytechnic, one of Singapore's foremost educational establishments. This partnership, which started in early 2024, focuses on producing collagen peptides derived from the skin of American bullfrogs. These peptides are unique and can be marketed either as complete molecules or as separate individual fragments, offering flexibility for various applications.
Advancements in Cosmeceuticals
Since completing the consultancy proposal in 2025, Cuprina has innovated a new methodology for generating these peptides. They have identified potential for cosmeceutical applications, which include skin moisturization and collagen remodeling. With the growing market for beauty products, Cuprina is actively exploring partnerships with cosmeceutical companies ready to capitalize on these new ingredients.
Research on 3D Printable Wound Care Solutions
Cuprina's second study is a result of a research collaboration with the esteemed Institute for Health Innovation and Technology at the National University of Singapore. This project started in late 2024 and aims to utilize bullfrog collagen peptides to produce 3D printable wound care dressings for diverse clinical applications. The funding for this ambitious project is provided by the National Additive Manufacturing Innovation Cluster Singapore, focusing on integrating technology and healthcare.
Enhancing Wound Healing through Innovation
The ongoing tests explore how integrating bullfrog collagen into microneedling patches can enhance the therapeutic effects on wound healing. These patches are designed with tiny needles to deliver active ingredients deeper into the skin. Successful results could significantly reduce inflammation and speed up recovery times for various wounds, presenting a breakthrough in wound management.
Production of Superior Collagen Peptides
The third initiative involves a collaboration with the Singapore Institute of Technology, initiated in early 2025. This research is focused on developing a premium powdered form of bullfrog collagen peptides, further serving the cosmeceutical market's demands. The goal is to create an innovative product that can be marketed independently or as specialized fragments.
Proven Efficacy of Bullfrog Collagen
Research indicates that collagen extracted from bullfrog skin forms a high-quality triple helix structure, which offers excellent biocompatibility and thermal stability, outperforming bovine collagen. Published data suggests this unique form of collagen achieved a remarkable 90% wound closure rate within 24 hours, compared to just 34% with traditional bovine sources, underlining the potential of bullfrog-derived products.
Future Market Prospects
Cuprina's Chief Executive Officer, David Quek, expressed optimism about these partnerships, emphasizing the significant market opportunities for bullfrog collagen peptides. The global market for collagen peptides is projected to grow substantially, increasing from approximately US$699 million to about US$922 million by 2028. This growth is driven by rising consumer awareness regarding health, especially among emerging markets in Asia, the Middle East, and beyond.
Cuprina is strategically positioned to leverage this market potential, contributing to advancements in various industries ranging from medical applications to cosmetics.
About Cuprina Holdings
Cuprina Holdings (Cayman) Limited is devoted to pioneering biomedical and biotechnology solutions aimed at enhancing quality of life. The company focuses on developing and commercializing health and beauty products derived from natural resources, ensuring compliance with international standards in their innovative medical devices.
Frequently Asked Questions
What is Cuprina Holdings focused on?
Cuprina Holdings specializes in biomedical and biotechnology innovations for chronic wound management, infertility, and beauty products.
What partnerships has Cuprina established for its research?
Cuprina has partnered with Republic Polytechnic, the National University of Singapore, and the Singapore Institute of Technology to advance their collagen peptide studies.
What makes bullfrog collagen unique?
Bullfrog collagen forms a pristine triple helix structure, offering superior biocompatibility and stability than traditional collagen sources such as bovine.
What applications can bullfrog collagen peptides be used for?
These peptides can be utilized in cosmeceuticals, wound care, and various medical, pharmaceutical, and nutraceutical products.
What is the growth potential of the collagen peptides market?
The global collagen peptides market is projected to grow significantly, reaching about US$922 million by 2028, propelled by increasing health awareness.
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