Amarin Corporation to Showcase New Insights at ESC 2025
Exciting Data Ahead at ESC 2025
Amarin Corporation plc (NASDAQ:AMRN), based in Dublin and Bridgewater, is gearing up for significant presentations at the upcoming European Society of Cardiology (ESC) Congress 2025. This event, set to take place from August 29 to September 1 in Madrid, will feature crucial new findings related to the cardioprotective effects of icosapent ethyl (IPE).
Understanding the Role of IPE
During the congress, the data presented will deepen the understanding of how IPE plays a vital role in reducing cardiovascular (CV) risks. It addresses various mechanisms, including inflammation, lipoprotein oxidation, and conditions associated with cardiovascular-kidney-metabolic (CKM) syndrome. The focus will be on findings from the REDUCE-IT trial and innovative mechanistic studies that explore the impact of eicosapentaenoic acid (EPA) on harmful cellular processes.
Key Insights from the REDUCE-IT Trial
Steven Ketchum, Ph.D., EVP and Chief Scientific Officer at Amarin, emphasized that the new analyses from the REDUCE-IT trial provide crucial insights supporting the beneficial role of IPE in various patient groups. The findings highlight the influence of IPE on hospitalizations related to CV risks and major adverse cardiovascular events (MACE), particularly concerning apolipoproteinB (ApoB) and triglyceride-rich lipoprotein-cholesterol (TRL-C) levels.
Innovative Presentations Focused on Cardiovascular Health
Amarin has designed a robust program for ESC 2025, including both oral presentations and moderated poster sessions. These presentations reflect the company’s unwavering commitment to advancing cardiovascular care and addressing persistent risks in patients globally. The event will also support educational initiatives led by top medical and scientific experts focused on residual cardiovascular risk.
Key Symposium by Amarin
Among the highlights is an Amarin-sponsored symposium titled, Addressing Residual Cardiovascular Risk: From Evidence To Experience, occurring on August 29 at 15:15 CET in Budapest, Hall 10. This session aims to consolidate knowledge and foster discussions around addressing ongoing cardiovascular risks.
Featured Research at ESC 2025
Amarin will showcase several impactful studies during the congress, each presented by respected academic collaborators:
Moderated Poster Presentations
- Icosapent Ethyl Reduces CVD Risk in Cardiovascular-Kidney-Metabolic Syndrome: REDUCE-IT CKM
Available August 29 at 16:15 CET, Station 10 – Research Gateway - Icosapent Ethyl Reduces Cardiovascular Risk Across Various Levels
Available August 30 at 8:15 CET, Station 12 – Research Gateway - Eicosapentaenoic Acid (EPA) Inhibited Lipoprotein(a) [Lp(a)] Oxidation
Available August 29 at 13:15 CET, Station 11 – Research Gateway
Oral Presentations Overview
- Effects of Icosapent Ethyl on Risk and Duration of Hospitalizations and Death in REDUCE-IT
Available August 30 at 8:15 CET, Sofia (North Convention Centre) - Eicosapentaenoic Acid (EPA) Effect on Inflammasome Activation
Available August 31 at 14:30 CET, Science Box 2 – Research Gateway
Amarin’s Commitment to Cardiovascular Innovation
As an innovative pharmaceutical entity, Amarin is dedicated to enhancing the understanding and treatment of cardiovascular diseases. The company's mission revolves around identifying and mitigating cardiovascular risks that persist even when patients are on conventional therapies.
About VASCEPA/VAZKEPA
VASCEPA (icosapent ethyl), the first prescription treatment approved by the FDA using solely this unique form of eicosapentaenoic acid, has been a game changer in fighting cardiovascular risks. Launched initially in 2013 for reducing triglyceride levels, it gained FDA approval in 2021 for reducing risk among patients at high cardiovascular risk, even with ongoing statin therapy.
Today, VASCEPA is prescribed extensively, with over twenty-five million prescriptions issued and remains crucial for patients in numerous countries, including the U.S., Canada, and various European nations. This widespread acceptance underscores its importance in modern cardiovascular treatment.
Frequently Asked Questions
1. What is the significance of the ESC 2025 event for Amarin?
ESC 2025 is a crucial platform for Amarin to present new research findings related to icosapent ethyl, showcasing its cardiovascular benefits and commitment to innovation in heart health.
2. How does Icosapent Ethyl work to reduce cardiovascular risks?
Icosapent ethyl works by addressing various mechanisms associated with cardiovascular risks, including inflammation and lipoprotein oxidation, which are critical factors in cardiovascular diseases.
3. What type of presentations will Amarin hold at ESC 2025?
Amarin will feature a mix of oral and moderated poster presentations highlighting new data and analyses, furthering understanding of IPE's cardiovascular benefits.
4. When is the Amarin-sponsored symposium at ESC?
The symposium titled, Addressing Residual Cardiovascular Risk: From Evidence To Experience, is scheduled for August 29 at 15:15 CET.
5. Where can I find more information about Amarin and its studies?
Additional information and updates can be found on Amarin's official website and its investor relations pages, which provide ongoing information about its research initiatives and product offerings.
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