Valneva Partners with Serum Institute to Enhance Vaccine Access

Valneva and Serum Institute Collaborate for Vaccine Accessibility

Valneva SE, a pioneering specialty vaccine company, has embarked on an important partnership with the Serum Institute of India (SII), the world's leading vaccine manufacturer, to enhance the availability of its chikungunya vaccine throughout Asia. This strategic collaboration marks a critical step toward addressing the growing public health challenges posed by chikungunya, particularly in low-and-middle-income countries (LMICs).

Addressing Public Health Needs in Asia

The partnership centers around an exclusive licensing agreement allowing SII to distribute Valneva’s single-shot chikungunya vaccine in several Asian markets, subject to obtaining necessary regulatory approvals. This initiative comes at a crucial time as India is experiencing one of its most severe chikungunya outbreaks, with rising cases reported recently.

The collaboration is further supported by a significant funding agreement worth $41.3 million from the Coalition for Epidemic Preparedness Innovations (CEPI), which emphasizes the commitment to improving health accessibility in the region.

Key Strategies and Goals of the Partnership

Under the terms of the agreement, both Valneva and SII will engage in a rapid technology transfer process for the manufacturing of the chikungunya vaccine. Valneva will supply the vaccine’s drug substance to SII, which will then take over the manufacturing and regulatory approval processes in India and beyond. Both organizations are equally dedicated to ensuring that the vaccine is made affordable for public health markets across LMICs.

Impact on the Current Chikungunya Outbreak

The urgency of this initiative is underscored by India's current public health crisis, characterized by a significant rise in chikungunya cases. With nearly 370,000 cases confirmed between early 2019 and mid-2024, swift action is vital. The partnership aims to expedite the deployment of the vaccine, ensuring that vulnerable populations have access to this much-needed preventive measure.

Valneva's Unique Position in Vaccine Development

Valneva positions itself as a leader in vaccine development, having created the world's first and only licensed chikungunya vaccine. This vaccine is currently approved in several regions, including Europe and Canada, for preventing diseases associated with the chikungunya virus among adults aged 18 and older. The commitment to expanding access to this vaccine is particularly relevant as regulatory reviews are underway to broaden its availability for younger populations.

Long-Term Vision for Public Health

Through this partnership, SII and Valneva are not just focusing on immediate needs but are also laying the groundwork for long-term public health strategies. The collaboration will enable SII to maintain a stockpile of 100,000 doses, allowing for prompt responses to potential future outbreaks within the region. This proactive approach ensures that essential resources are available when they are needed most.

Expert Opinions on the Collaboration

Leaders from both Valneva and SII have expressed their enthusiasm about the partnership. Thomas Lingelbach, CEO of Valneva, emphasized the international public health priority of addressing chikungunya outbreaks. Adar Poonawalla, CEO of SII, highlighted the commitment to delivering effective and accessible vaccines to communities facing health challenges.

The Global Challenge of Chikungunya

Chikungunya, a viral disease transmitted by mosquito bites, has emerged as a significant global health threat. As the disease spreads across continents, it brings with it debilitating symptoms, including severe joint pain and other flu-like symptoms. The collaboration between Valneva and SII represents a strong response to this expanding health issue, utilizing both organizations' expertise in vaccine development and distribution.

Future Prospects and Collaborations

Valneva's efforts to expand its vaccine access beyond Asia are supported by previous collaborations, including a partnership with Brazil's Instituto Butantan aimed at distributing the vaccine across the Americas. This multi-national approach underscores the company's commitment to fighting infectious diseases on a global scale, bolstered by collaboration with key stakeholders.

Frequently Asked Questions

What is the purpose of Valneva's collaboration with the Serum Institute?

The collaboration aims to enhance access to Valneva's chikungunya vaccine in Asia, particularly targeting low-and-middle-income countries affected by outbreaks.

How does the chikungunya vaccine work?

Valneva's chikungunya vaccine is designed to prevent diseases caused by the chikungunya virus by inducing an immune response in individuals who receive the shot.

What are the expected benefits of this partnership?

This partnership is expected to accelerate the availability of the vaccine in regions currently experiencing chikungunya outbreaks and improve public health outcomes.

Is the chikungunya vaccine approved for younger populations?

Currently, the vaccine is approved for individuals 18 years and older, with ongoing reviews to potentially expand its availability to those aged 12 and older.

How can the public access the chikungunya vaccine?

Once regulatory approvals are obtained, the vaccine will be made available through public health markets, particularly in low-and-middle-income countries where it is needed most.

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