TerSera Discusses Game-Changing Findings on Goserelin for Breast Cancer

Introduction to Goserelin in Breast Cancer Treatment

TerSera Therapeutics LLC has recently made notable strides in the fight against breast cancer with its groundbreaking presentation on goserelin. The innovative analyses showcased the treatment patterns of goserelin, a medication crucial in managing breast cancer, particularly in young women. This significant announcement took place at a prestigious symposium centered on quality care in oncology.

Study Overview and Objectives

The primary aim of this extensive study was to delve into the treatment experiences of female patients diagnosed with breast cancer who were treated using either the 3.6 mg or 10.8 mg doses of goserelin. By leveraging real-world evidence (RWE), TerSera set out to paint a clearer picture of how goserelin is utilized in clinical practice across the United States.

Methodology and Data Collection

To conduct this retrospective analysis, a comprehensive review of electronic health records through TriNetX was employed. This global healthcare research network provided valuable insights into the treatment patterns from January 2017 to December 2022, with follow-up continuing until March 15, 2024. The study garnered data from 3,620 patients, revealing how they interacted with goserelin therapies.

Insights on Patient Demographics

Among the identified patients, a substantial majority, 2,870, received the 3.6 mg dosage of goserelin. Additionally, 410 patients were treated with the 10.8 mg formulation, while 340 transitioned from the lower dose to the higher. Analyses captured vital patient demographics, adherence to treatment regimens, and utilization of healthcare resources.

Expert Commentary on Findings

Lonnie Brent, Pharm.D., who serves as the Senior Vice President of Medical and Scientific Affairs at TerSera Therapeutics, emphasized the significance of these findings. He remarked, "For young women with hormone-sensitive breast cancer at high risk of relapse, suppression of ovarian function is an essential component of their long-term treatment plan. This real-world evidence presented at the symposium enhances our comprehension of existing treatment patterns for young women receiving goserelin."

Regulatory Approvals and Indications

Goserelin, marketed as ZOLADEX, has received approval for various medical indications. The 3.6 mg and 10.8 mg formulations primarily manage hormone-sensitive conditions, including advanced breast and prostate cancers. Notably, ZOLADEX 3.6 mg also finds application in treating endometriosis and thinning the endometrium prior to surgical procedures.

Safety Profile and Adverse Effects

Like all therapeutic agents, goserelin comes with a spectrum of potential side effects. Among the most commonly reported reactions in clinical trials include hot flashes, decreased libido, and various symptoms associated with hormonal inhibition. Healthcare providers are encouraged to closely monitor patients for any adverse events and adjust treatment plans accordingly.

Importance of Ongoing Research

The outcomes from the ASCO symposium highlight an essential drive toward understanding how goserelin influences treatment outcomes. Research continues to shine a spotlight on how young patients manage breast cancer and the implications of treatment choices on long-term health and survivorship.

Conclusion on Treatment Patterns

As TerSera Therapeutics propels forward, the insights gained from this study will undoubtedly inform clinical strategies and patient care standards. The commitment to bolster understanding around treatment pathways for breast cancer using goserelin is not just a corporate objective; it is a promise to the many women affected by this diagnosis.

Frequently Asked Questions

What is goserelin?

Goserelin is a luteinizing hormone-releasing hormone agonist used to treat various hormone-sensitive cancers, including breast and prostate cancer.

What were the findings on goserelin treatment patterns?

The study revealed insights into how goserelin is utilized among young women with breast cancer, with a focus on adherence and healthcare resource utilization.

Why is ovarian function suppression important?

Suppressing ovarian function can significantly impact the long-term treatment outcomes for young women with hormone-sensitive breast cancer.

What side effects are associated with goserelin?

Common side effects include hot flashes, decreased libido, and mood changes, among others, which are associated with hormone therapy.

Where can I find more information about TerSera Therapeutics?

Information about TerSera and its ongoing research can be found on their official website.

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