Somite Therapeutics Partners with OmniaBio for Cell Therapy
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Collaboration Announcement: Somite Therapeutics and OmniaBio
The partnership aims to propel cell replacement therapy targeting a severe genetic disorder.
Somite Therapeutics and OmniaBio Inc. have teamed up to advance cell therapy production for Duchenne muscular dystrophy (DMD). This collaboration seeks to optimize the development of SMT-M01, a leading-edge therapy that has the potential to restore muscle function in patients suffering from this debilitating disease.
Professor Peter Zandstra, portraying significant enthusiasm for the collaboration, stated that it promises long-term advancements not just for this program but the entire field of cell therapy. He emphasized that Somite’s innovative use of artificial intelligence in the discovery and optimization of cell therapies opens up exciting prospects, particularly in enhancing the effectiveness and cost-efficiency of such treatments.
Duchenne muscular dystrophy is a severe genetic disorder that causes progressive muscle degeneration and has no known cure. This collaboration aims to leverage both companies' expertise to develop a sophisticated cell replacement therapy that can slow down the progression of the disease and significantly improve the quality of life for patients diagnosed with DMD.
Dr. Kristy Brown from Somite Therapeutics highlighted that working alongside OmniaBio offers invaluable iPSC technology experience, ensuring efficient progress in their DMD program. This partnership inspires confidence in the development process and regulatory compliance necessary to expedite valuable therapies to those in need.
As part of the partnership, OmniaBio will manage several critical processes, including master cell banking, pluripotent stem cell differentiation, and optimization of harvesting conditions for drug production. This systematic approach is rooted in their significant experience in induced pluripotent stem cell technology.
Looking ahead, Dr. Micha Breakstone, Somite Therapeutics' CEO, suggested that they anticipate entering phase one/two trials within the next eighteen to twenty-four months. He expressed excitement about the collaboration's role in transforming patient outcomes and advancing stem cell biology.
Mitchel Sivilotti, President and CEO of OmniaBio, also conveyed optimism regarding how their combined efforts could lead to transformative innovations in treatment for DMD patients worldwide. He noted that their deep expertise in iPSC technology, combined with an emerging focus on AI-powered innovations, would play a pivotal role in improving manufacturing processes and accelerating clinical translation.
About Somite Therapeutics
Founded recently, Somite Therapeutics is dedicated to revolutionizing stem cell biology by merging artificial intelligence with cell therapy research. Their unique AI-driven platform, known as AlphaStem, aims to create human tissues for cell therapies focusing on various diseases including diabetes, obesity, and muscular dystrophies. Somite’s current projects include the promising SMT-M01 for DMD and SMT-B01 targeting metabolic disorders. The company has already raised over $10 million to enhance their groundbreaking initiatives.
Management Team Overview:
- Micha Breakstone, PhD: CEO and Co-founder
- Jonathan Rosenfeld, PhD: CTO and Co-founder
- Carl Morris, PhD: Chief Scientific Officer
- Kristy Brown, PhD: SVP Translational Development
About OmniaBio
OmniaBio Inc. excels as a cell and gene therapy contract development and manufacturing organization (CDMO) focused on innovative regenerative medicine solutions. They possess substantial expertise in manufacturing immune cell-based therapies along with advanced gene therapy applications. With ongoing enhancements in their clinical production capabilities, OmniaBio stands ready to deliver on the escalating demand for advanced therapeutic solutions across the globe.
Frequently Asked Questions
What is the purpose of Somite Therapeutics and OmniaBio's collaboration?
The collaboration aims to advance the development of SMT-M01, a cell replacement therapy targeting Duchenne muscular dystrophy.
How does AI play a role in this partnership?
Somite utilizes AI technology to enhance the discovery and optimization processes for cell therapy manufacturing, improving efficiency and effectiveness.
What is Duchenne muscular dystrophy?
DMD is a severe genetic disorder characterized by progressive muscle degeneration and weakness, with no known cure available.
When do the companies expect to start clinical trials?
The initial phase one/two clinical trials for SMT-M01 are anticipated to begin within 18 to 24 months.
What other programs does Somite Therapeutics focus on?
Besides SMT-M01 for DMD, Somite Therapeutics is also developing SMT-B01 aimed at metabolic disorders.
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