Salarius Pharmaceuticals Achieves Nasdaq Compliance Again

Salarius Pharmaceuticals Regains Key Nasdaq Listing Compliance
Salarius Pharmaceuticals, Inc. (Nasdaq: SLRX) has made an important announcement regarding its compliance with Nasdaq listing standards. Recently, the company received notification from the Nasdaq Stock Market, confirming its adherence to the necessary listing requirements. This positive update marks a significant milestone in Salarius' journey and reinforces its strategic plans moving forward.
Significant Steps Towards Merger with Decoy Therapeutics
On October 10, 2025, Salarius became compliant with Nasdaq Listing Rule 5550(b)(1), following a prior announcement of compliance with Listing Rule 5550(a)(2). This achievement is particularly timely as Salarius anticipates a merger with Decoy Therapeutics, a preclinical biopharmaceutical company focusing on innovative peptide conjugate therapeutics.
Mark J. Rosenblum, acting CEO and CFO of Salarius, expressed enthusiasm about the company's status: “Salarius is now fully compliant with all Nasdaq listing requirements, marking another critical step in our planned merger with Decoy Therapeutics.” With this consolidation, Salarius aims to position itself as a leader in the biopharmaceutical industry while maximizing its potential portfolio impact.
Insights into the Merger Agreement
The merger agreement between Salarius and Decoy Therapeutics is designed to enhance the combined entity's capabilities in developing next-generation therapeutics. This collaboration will leverage Decoy’s remarkable IMP3ACT™ platform, which is engineered for rapid computational design and advancement of peptide-based therapies.
Decoy’s product candidates are targeting pressing needs within respiratory infectious diseases and gastrointestinal oncology, promising groundbreaking solutions for these areas. Furthermore, Salarius’ proprietary oral small molecule protein degrader, SP-3164, will also be integrated into the pipeline, combining forces to form powerful proteolysis targeting chimeras (PROTACS).
Future Directions and Expectations
The merged entity is poised to make significant advancements within the coming years. Decoy Therapeutics plans to propel its foremost asset, a pan-coronavirus antiviral, towards an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA). Alongside this, the pipeline will also address urgent issues related to influenza and RSV, alongside efforts to advance peptide cancer therapeutics.
In conjunction, Salarius continues to support the clinical investigation of seclidemstat at MD Anderson Cancer Center. This study is pivotal in evaluating the drug's effectiveness for myelodysplastic syndrome and treatment-resistant chronic myelomonocytic leukemia, highlighting Salarius’ commitment to oncology-focused therapies.
About Salarius Pharmaceuticals
Salarius Pharmaceuticals is dedicated to innovating solutions for patients battling cancer, with its lead candidate, seclidemstat, currently assessed in clinical trials. Furthermore, SP-3164 stands as a targeted approach in oncology, optimizing therapeutic strategies for patients requiring novel options.
About Decoy Therapeutics
Decoy Therapeutics operates at the cutting edge of biotechnology, utilizing advanced machine learning and AI to develop effective drug candidates that address critical health concerns. Their innovative pipeline, which emphasizes respiratory viral infections and gastroenterological cancers, shows great promise in altering treatment landscapes.
Frequently Asked Questions
1. What is the significance of Salarius regaining compliance with Nasdaq?
Regaining compliance signifies that Salarius fulfills the necessary financial and operational standards to remain listed on the Nasdaq, allowing it to pursue further growth opportunities.
2. How does the merger with Decoy Therapeutics benefit Salarius?
The merger will enhance Salarius’ capabilities to produce innovative therapeutics and expand its market reach, leveraging Decoy's technology and expertise.
3. What are the primary focuses of Decoy Therapeutics' product pipeline?
Decoy Therapeutics concentrates on developing treatments for respiratory infectious diseases and gastroenterological cancers, addressing significant unmet medical needs.
4. What role does Salarius’ SP-3164 play in the combined company’s strategy?
SP-3164 is intended to enhance the therapeutic offerings of the combined company, particularly through its role in proteolysis targeting chimeras (PROTACS).
5. When does Salarius plan to file for an Investigational New Drug application?
Decoy expects to advance its leading asset and file for an IND application for its pan-coronavirus antiviral within the next year, as part of its future drug development strategy.
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