Rhythm Pharmaceuticals to Speak at Healthcare Conference
Rhythm Pharmaceuticals to Present at Upcoming Conference
Rhythm Pharmaceuticals, Inc. (NASDAQ: RYTM), a biopharmaceutical company dedicated to improving the lives of patients with rare neuroendocrine diseases, has announced that its Chair, President, and Chief Executive Officer, Dr. David Meeker, will participate in a fireside chat at the Wells Fargo Healthcare Conference. This event is scheduled to take place at Encore Boston Harbor, featuring a comprehensive discussion on their innovative treatments at 3:45 p.m. ET on September 5, 2024.
Live Webcast Available
The fireside chat will be available for live streaming under the "Events & Presentations" section in the Investor Relations section of the company’s website. Following the live event, a replay will also be accessible for 30 days, allowing those who cannot attend the opportunity to catch up on the insights shared during the presentation.
About Rhythm Pharmaceuticals
Rhythm Pharmaceuticals is at the forefront of biopharmaceutical advancements, focusing on rare neuroendocrine diseases. Its flagship product, IMCIVREE (setmelanotide), plays a pivotal role in treating hyperphagia and severe obesity. The FDA has already approved setmelanotide for chronic weight management in patients aged six and older, who have specific genetic forms of obesity. These genetic issues include POMC, PCSK1, or LEPR deficiencies, which can be confirmed through genetic testing.
Regulatory Approvals Across Regions
In addition to its approval in the U.S., both the European Commission (EC) and the UK's Medicines & Healthcare Products Regulatory Agency (MHRA) have authorized setmelanotide for treating obesity and controlling hunger for certain patient populations. This includes those genetically confirmed to have Bardet-Biedl syndrome and associated deficiencies. The EC specifically allows this medication for children as young as 2, demonstrating Rhythm's commitment to pediatric care.
Broad Clinical Development Programs
Alongside its approved therapy, Rhythm is expanding its clinical development for setmelanotide into other rare diseases. The company is also exploring investigational MC4R agonists like LB54640 and RM-718, as well as developing a suite of small molecules aimed at treating congenital hyperinsulinism. This diverse pipeline illustrates Rhythm's ambitious approach to addressing significant unmet medical needs.
Setmelanotide Indications and Limitations
In the U.S., setmelanotide is indicated for chronic weight management in both adult and pediatric patients with specific genetic conditions tied to obesity. It's critical to note that setmelanotide is not advised for patients with non-genetic obesity or those with benign genetic variants. Proper diagnosis through an FDA-approved test is necessary before commencing treatment.
Considerations and Precautions
Potential patients should be aware of critical safety information regarding setmelanotide. It is contraindicated in individuals who have a serious hypersensitivity to the product. There are important warnings associated with the drug, including risks of increased skin pigmentation, monitoring requirements for heart rate and blood pressure, and potential psychological effects, such as depression or suicidal thoughts. Ongoing assessment is essential for individuals undergoing treatment, especially in pediatric populations, to monitor growth and side effects.
Adverse Reactions and Specific Populations
Reported adverse reactions associated with setmelanotide include skin hyperpigmentation, injection site reactions, nausea, and more. During the course of treatment, lactating individuals should consult their healthcare provider about the risks associated with breastfeeding while using this medication.
Contact Information for Rhythm Pharmaceuticals
For any inquiries or to report suspect adverse reactions, Rhythm Pharmaceuticals encourages individuals to reach out directly. David Connolly, Head of Investor Relations and Corporate Communications, can be contacted at 857-264-4280 or via email.
Frequently Asked Questions
What is Rhythm Pharmaceuticals known for?
Rhythm Pharmaceuticals is a biopharmaceutical company focused on developing treatments for rare neuroendocrine diseases, using innovative therapeutics like setmelanotide.
Who will be presenting at the Wells Fargo Healthcare Conference?
Dr. David Meeker, the Chair, President, and Chief Executive Officer of Rhythm Pharmaceuticals, will be making a presentation at the conference.
How can I access the conference webcast?
The webcast of the fireside chat can be accessed through the "Events & Presentations" section of Rhythm's Investor Relations website.
What approvals does setmelanotide have?
Setmelanotide has received FDA approval for chronic weight management in specific obesity types, and it is also authorized by the European Commission and MHRA for certain genetic conditions related to obesity.
What should patients be cautious of while taking setmelanotide?
Patients should be aware of potential adverse reactions and the need for ongoing medical supervision during treatment, especially regarding psychological effects and monitoring of physical health.
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