r/Livimmune
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1h ago
1975Bigstocks
New NIH HIV Study Using Leronlimab
https://reporter.nih.gov/search/c6Mb_tF0cUavw...s/11537080
Just came across this and thought it was interesting. I don’t remember seeing it discussed before.
There’s a new nih funded research project led by Koki Morizono at ucla looking at a different way to provide longer term anti hiv antibodies. i could be wrong but it seems somewhat similar to the goal that ohsu/sacha is working on but they’re attacking it differently. Sacha is using aav vectors vs. this group genetically modifying B cells so they basically become little antibody factories and keep producing LL if i understand it correctly.
In any event, what caught my attention is that LL is specifically one of the two antibodies they chose to test. This appears to still be very early preclinical research in mice so it's a ways off. I don't recall any mention of us publicly having a relationship with this ucla group, so as far as I know this appears to be independent research which is totally cool. just adds to the growing evidence that LL is truly a remarkable drug. They clearly see something promising.
Total project funding = $5,927,367
•
1h ago
1975Bigstocks
New NIH HIV Study Using Leronlimab
https://reporter.nih.gov/search/c6Mb_tF0cUavw...s/11537080
Just came across this and thought it was interesting. I don’t remember seeing it discussed before.
There’s a new nih funded research project led by Koki Morizono at ucla looking at a different way to provide longer term anti hiv antibodies. i could be wrong but it seems somewhat similar to the goal that ohsu/sacha is working on but they’re attacking it differently. Sacha is using aav vectors vs. this group genetically modifying B cells so they basically become little antibody factories and keep producing LL if i understand it correctly.
In any event, what caught my attention is that LL is specifically one of the two antibodies they chose to test. This appears to still be very early preclinical research in mice so it's a ways off. I don't recall any mention of us publicly having a relationship with this ucla group, so as far as I know this appears to be independent research which is totally cool. just adds to the growing evidence that LL is truly a remarkable drug. They clearly see something promising.
Total project funding = $5,927,367
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