True, In our phase 1b/2 trial , first 9 patient
Post# of 152049
In our phase 1b/2 trial , first 9 patients were
3:3:3
first 3 started on 350 mg , if no problem for 42 days , after 2 Circulating cancer cells tests ,the
next 3 patients took 525 mg , again for 42 days,
After that all patients took 700 mg.
I just don't remember now , after FDA OK for us 700 mg dose , if all the patients they changed to 700 mg.
I just don't remember .
If not , then 6 patients were on less then 700 mg.
But in our CRC protocol , they also starting on different doses , but after safety committee will find no problems , patients will be change to 700 mg.
This I don't remember exactly with our previous trial.

