October 9th 2024 Jonah Sacha presented in Lima Peru.
https://programme2024.hivr4p.org/Abstract/Abs...actid=1904
summary page of conference session on Oct 9 by AUTHOR Dieter Kenneth Mielke
"HIGHLIGHTS
The session began with Dr. Sasha presenting an infant NHP study using a promising combination of an anti-CCR5 antibody, two broadly neutralizing antibodies (bnAbs) and antiretroviral therapy (ART) as a potential strategy to eradicate the reservoir. No rebound, cell-associated viral DNA or viral DNA in lymph nodes was found, even following CD8 depletion, suggesting bnAbs synergized with CCR5 blockade to eliminate the viral reservoir. " (highlights continued for the other studies at conference)
"CRITICAL ASSESSMENT
The data demonstrating eradication of the reservoir represents a promising strategy for cure from HIV in infant populations acquiring HIV through vertical transmission. Further studies will need to be completed to understand if the findings translate into adults." (assessment continued for the other studies at conference)
https://programme2024.hivr4p.org/Abstract/Abs...actid=1904
summary page of conference session on Oct 9 by AUTHOR Dieter Kenneth Mielke
"HIGHLIGHTS
The session began with Dr. Sasha presenting an infant NHP study using a promising combination of an anti-CCR5 antibody, two broadly neutralizing antibodies (bnAbs) and antiretroviral therapy (ART) as a potential strategy to eradicate the reservoir. No rebound, cell-associated viral DNA or viral DNA in lymph nodes was found, even following CD8 depletion, suggesting bnAbs synergized with CCR5 blockade to eliminate the viral reservoir. " (highlights continued for the other studies at conference)
"CRITICAL ASSESSMENT
The data demonstrating eradication of the reservoir represents a promising strategy for cure from HIV in infant populations acquiring HIV through vertical transmission. Further studies will need to be completed to understand if the findings translate into adults." (assessment continued for the other studies at conference)
16
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