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“At one time I thought of tracking down the comp

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Post# of 155103
(Total Views: 737)
Posted On: 06/02/2024 8:00:18 PM
Posted By: Plotinus
Re: ohm20 #144137
“At one time I thought of tracking down the complete pathways of everything connected to CCR5 but that could take a couple of years.”

OHM is right, it’s a rabbit hole and a PhD Thesis for Alice if she makes it out alive.

Based on everything I have read and coming from a medical background, for anyone interested in teasing out the connections you will find it invaluable to get a basic understanding of immunology first and then leverage the kind of articles that put a prism on the process. For example, I found this Nature article very useful and you will begin to understand how central NF-κB is to the inflammatory process. Take time to absorb figure 1, which shows the relationship to chemokines.

“NF-κB signaling in inflammation”
https://www.nature.com/articles/sigtrans201723

Failing this approach, matriculate with Alice on a PhD track in immunology.





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