Brilacidin Vs Rabies Brilacidin vs. Rabies Rab
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Brilacidin vs. Rabies
Rabies virus replicates along muscle and nerve tissue. It will eventually reach the major nerves and enter the CSF (Cerebral Spinal Fluid).
Brilacidin if given in conjunction with Ketamine has a synergistic effect of rewiring the neurons thus preventing paralysis caused by the toxic effect of surface proteins on the rabies virus and autonomic dysfunction. These surface proteins in rabies resemble rattlesnake venom and the rabies virus inserts itself in between neurons.
Ketamine “rewires” around the rabies virus thus preventing a shut down of the autonomic system
The proteins produced on the surface of the rabies virus are perfect for producing a B cell epitope.
Let me explain B cell epitopes: I will keep it light I promise.
First the rabies glycoprotein is the only exposed protein which is inserted in the viral lipidie envelope. This 65-67 kda (kilo Daltons- BBB allows 200~400 Da) protein is a N-glycosilated transmembrane protein forming trimers on the viral surface. It has been identified as the major pathogenicity determinant, playing a role in the budding, viral axonal transport during infection, apoptosis and immune evasion. It is also the major antigen responsible for the protective immune response and it is been used in commercial recombinant vaccines. Brilacidin is going to shred this glycoprotein that is on the surface envelope which this exposed protein is.
The B cell epitope is the result of an antigen combining with an analyte (small fraction) of the surface glycoprotein.
Brilacidin is going to strip these toxic residues of the glycoprotein, antigens will attach to them, and then antibodies will be made.
Here is the power in all of this Brilacidin is going to remove the surface envelope thus remove 95% of the viral load in one hour.
B cell Epitope: The antigenicity of proteins resides in different types of antigenic determinants known as continuous and discontinuous epitopes, cryptotopes, neotopes, and mimotopes. All epitopes have fuzzy boundaries and can be identified only by their ability to bind to certain antibodies. Antigenic cross-reactivity is a common phenomenon because antibodies are always able to recognize a considerable number of related epitopes. This places severe limits to the specificity of antibodies. Antigenicity, which is the ability of an epitope to react with an antibody, must be distinguished from its immunogenicity or ability to induce antibodies in a competent vertebrate host. Failure to make this distinction partly explains why no successful peptide-based vaccines have yet been developed. However, when the body makes it own antibodies they are not naive and specifically match the bodies antigen factors.
This why a one size fits all vaccine doesn’t work. Think about type and cross match or
blood type and antigen factor. Blood that matches this week can be rejected next week from the same donor. This never happens when you use your own blood. Thus when you make antibodies they are a perfect match for your immune system and are not naive antibodies.
Once B lymphocytes spot the antigen (antibody generators), they begin secreting antibodies. Antibodies are special proteins that lock on to specific antigens.
Each B cell makes one specific antibody. For instance, one might make an antibody against the bacteria that cause pneumonia, and another might recognize the common cold virus.
Antibodies are part of a large family of chemicals called immunoglobulins, which play many roles in the immune response:
• Immunoglobulin G (IgG) marks microbes so other cells can recognize and deal with them( D3 is a immuno modulator and kicks all Ig responses up a few notches )
• IgM specializes in killing bacteria
• IgA congregates in fluids, such as tears and saliva, where it protects gateways into the body
• IgE protects against parasites and plays a role in allergies
• IgD stays bound to B lymphocytes, helping them start the immune response
Brilacidin will make millions of different antibodies in one hour and that is why it is so effective.
Your body will make perfect “antibodies” and you will self inoculate with non naive antibodies.
My goal is to save 100 rabid dogs by Christmas.