Baldness and leronlimab I have alopecia areata
Post# of 148154
I have alopecia areata on the disease list which is caused by autoimmunity. But newer research may mean that leronlimab could possibly treat testosterone caused baldness which is the most prevalent type of baldness.
Researchers have found that the driving force behind that type of baldness is an overexpression of Transforming Growth Factor Beta (TGF-b). A large amount kills off hair follicles. A small amount can induce the ever present stem cells to convert to new hair follicles. Leronlimab downregulates overexpression of TGF-b. TGF-b is also implicated in kidney disease, NASH, heart disease, Alzheimer's, cancer and other diseases.
The End of Baldness? The Chemical Controlling Life and Death in Hair Follicles Identified
In this Covid leronlimab study TGF-b was reduced by 73%.
Disruption of the CCL5-RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19