1 year 500 Placebo 500 350mg weekly 500 700mg

1 year

500 Placebo
500 350mg weekly
500 700mg weekly

minimum baseline cT1 inclusion 800 msec to be allowed into study
obtain average Placebo baseline cT1 level

break each dosage (350 & 700mg) subgroup down into:
<875 msec;
876 msec < suba < 950 msec;
951 msec < subb < 1050 msec;
> 1051 msec;