I think, don’t know, that the lower interim analysis is to get trial data out quickly which should help full enrollment. If we have 40 sites, some might only have 1-2 patients and they might be placebo. The doctors might feel this trial is not worth the effort, unless they see the results as a whole and then realize the must enroll as many as possible as quickly as possible. It also will help for us to to make sure we are getting the right patients and don’t end up with skewed data.