It doesnt matter however getting confirmation that the first patient derisks any chances that the trail would not even happen, it also takes one piece of FUD of the plate of the bashers. I know for one that now the clock starts…. How quickly can we get the 40% of trail full. I look forward to updates as they come on enrollment numbers. I think the excitement factor will start to show in SP in the coking weeks/months. I have heard some say that all that matters is the end results of trial…. I disagree i think the trial starting… the trial progressing… the trial getting close to 40% enrollment will all be factors in driving the SP up. This should happen all the while we get updates on Long haulers, Nash, Cancer and HIV BLA.