Did you understand the interaction between Il-10 a

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Did you understand the interaction between Il-10 and CCR5 expression. CCR5 expression up-regulated by anti inflammatory IL-10.

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IL-10 can both upregulate and downregulate CCR5, I can't remember off-hand which states cause either. There is also a feedback loop where CCR5 will regulate IL-10. I had to string together bits from several papers to figure that one out but I never wrote down the pathway.