This is important, please read all as time permits.....
(Philippines Chronology of events supporting probability of their approval)
konks wrote:
Calstang, I agree with your comment that the doctors in the Philippines know what made the difference for former Pres Estrada, regardless of the news. Legislator Ms Herrera is working it also from the govt side , so something good will come out of this IMO. It would be good to hear something about the 28 folks and assuming we get the news we expect from them, more orders will come in and soon it should start to feel like Walmart at Christmastime around here. Those doctors in the Philippines are going say, "holy crap, this stuff actually works!".
my response:
Philipine doctors were talking about and wanting Leronlimab some time ago, before several important compelling events happened....
1) a patient in the UK who had received remdesivir and other SOC and who had been on ECMO, after more than 65 days on ECMO, finally some bold person suggests Leronlimab. A couple days later, he's taken off ECMO, a couple of days later, he is doing well and leaves ICU. A couple of days later, he walks out of the hospital. For us who know, well, not that really of a big deal, we already saw that with 70 patients who received LL in about April of 2020 under eIND.
2) this video appears, Philippine doctors talkng about how great leronlimab is, agreeing the Philippines should get LL. They are impressed with compelling 82% reduction in deaths vs SOC at 14 days in LL s/c trial. https://www.youtube.com/watch?v=bP5Wnnqpr2I&t=56s
3) a critical patient in the Philippines on ventilation, had been given all SOC drugs including remdesivir, he remained on vent for many weeks. He is given LL and is taken off vent after 4 days, out of ICU a few days later, a week or so later walks out of hospital.
4) next, Pres Estrada enters hospital in severe/critical condition. He is placed on a ventilator and given remdesivir, and other SOC drugs and leronlimab. A few days laters, he's off the vent. Technically, scientifically no way to know for certain that LL was the reason he progressed (remdeathsivir or LL?) , but doctors in Philippines know for 2 reasons. a) 1-3 above and b) they've been observing the lack of efficacy from remdesivir in critical cv19 patients for many months, so they know as we do, it was leronlimab.
5) next the Philiipines negotiates an increase in their "allotment" of Leronlimab from Cytodyn up from 100,000 vials to 200,000 vials
6) next the Philippines legislature presents a bill/motion to enable purchasing of & stocking of, cv19 drugs, prior to a specific patient need, due to 5 to 6 days shipping delay, in fact a patient for whom they'd ordered LL, died before LL arrived.
7) next the Philippines orders enough Leronlimab under "Compassionate Use" for 28 Critical patients
next, 2 days ago, this video released expressing that the Philippines legislature has taken it up a level in demanding leronlimab s/c and ivermectin m/m be approved to save lives of Philippine citizens.
https://www.youtube.com/watch?v=N9h8wFNRdSs
9) then, today, Pres Estrada fully recovers and is released out of the hospital, he is alive, recovered, leronlimab saved his life. Folks say not sure if it was leronlimab or combo of drugs, but their doctors definetely know it's LL.
10) we anxiously await either or, or both for positive results from recovering Manila28Critcals getting shots of leronlimab and/or Philippine approval of leronlimab, which should be a significant sparke/catalyst to get things going.
(Philippines Chronology of events supporting probability of their approval)
konks wrote:
Calstang, I agree with your comment that the doctors in the Philippines know what made the difference for former Pres Estrada, regardless of the news. Legislator Ms Herrera is working it also from the govt side , so something good will come out of this IMO. It would be good to hear something about the 28 folks and assuming we get the news we expect from them, more orders will come in and soon it should start to feel like Walmart at Christmastime around here. Those doctors in the Philippines are going say, "holy crap, this stuff actually works!".
my response:
Philipine doctors were talking about and wanting Leronlimab some time ago, before several important compelling events happened....
1) a patient in the UK who had received remdesivir and other SOC and who had been on ECMO, after more than 65 days on ECMO, finally some bold person suggests Leronlimab. A couple days later, he's taken off ECMO, a couple of days later, he is doing well and leaves ICU. A couple of days later, he walks out of the hospital. For us who know, well, not that really of a big deal, we already saw that with 70 patients who received LL in about April of 2020 under eIND.
2) this video appears, Philippine doctors talkng about how great leronlimab is, agreeing the Philippines should get LL. They are impressed with compelling 82% reduction in deaths vs SOC at 14 days in LL s/c trial. https://www.youtube.com/watch?v=bP5Wnnqpr2I&t=56s
3) a critical patient in the Philippines on ventilation, had been given all SOC drugs including remdesivir, he remained on vent for many weeks. He is given LL and is taken off vent after 4 days, out of ICU a few days later, a week or so later walks out of hospital.
4) next, Pres Estrada enters hospital in severe/critical condition. He is placed on a ventilator and given remdesivir, and other SOC drugs and leronlimab. A few days laters, he's off the vent. Technically, scientifically no way to know for certain that LL was the reason he progressed (remdeathsivir or LL?) , but doctors in Philippines know for 2 reasons. a) 1-3 above and b) they've been observing the lack of efficacy from remdesivir in critical cv19 patients for many months, so they know as we do, it was leronlimab.
5) next the Philiipines negotiates an increase in their "allotment" of Leronlimab from Cytodyn up from 100,000 vials to 200,000 vials
6) next the Philippines legislature presents a bill/motion to enable purchasing of & stocking of, cv19 drugs, prior to a specific patient need, due to 5 to 6 days shipping delay, in fact a patient for whom they'd ordered LL, died before LL arrived.
7) next the Philippines orders enough Leronlimab under "Compassionate Use" for 28 Critical patients
next, 2 days ago, this video released expressing that the Philippines legislature has taken it up a level in demanding leronlimab s/c and ivermectin m/m be approved to save lives of Philippine citizens. https://www.youtube.com/watch?v=N9h8wFNRdSs
9) then, today, Pres Estrada fully recovers and is released out of the hospital, he is alive, recovered, leronlimab saved his life. Folks say not sure if it was leronlimab or combo of drugs, but their doctors definetely know it's LL.
10) we anxiously await either or, or both for positive results from recovering Manila28Critcals getting shots of leronlimab and/or Philippine approval of leronlimab, which should be a significant sparke/catalyst to get things going.
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