WE seem to have a lot of ways to define a failure.
Post# of 148164
A Pulsating P-Value in and of itself does NOT save a life...it's a construct ..a guide......BIG NEWS......WE are in a Pandemic/Endemic.........AS a doctor....you want access to the REMEDY and NOT leave to chance the possibility that your patient could possibly end up with the SHORT end of the stick.....Totally UNDERSTANDABLE......How do you establish a trial where the cat is out of the bag already ...the drug works...NO mystery.....WHAT Physician will knowingly allow his patient to be part of THAT scenario.......Don't we have enough damage on exhibit....to show demonstrable proof that the Molecule is effective...without putting more lives at risk?.... All the while "do no harm"...Am I chasing my tail here?