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Disagree. Keep in mind that they had about 30 p

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Post# of 155026
(Total Views: 706)
Posted On: 01/06/2021 5:31:30 PM
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Posted By: lorbas
Re: IndexGuy #71543
Disagree.

Keep in mind that they had about 30 patients on placebo only (out of ~90 without any SOC add-ons) in Spring before the protocol was changed to incorporate SOC add-ons... Not unrealistic that a lot of those died (e.g. 50%, which would already account for 15 events in the placebo group.

The worst distribution allowed to achieve stat sig would be ~37 deaths in placebo (28,4%), ~50 in LL arm (19,2%). That's about 33% RRR.

Not sure whether all those 87 deaths happened within the 28 days timeframe though.

Exciting 2-3 weeks ahead for sure


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