COVID>Brain: Oct. 13, 2020 SARS-CoV-2 infect
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Posted On: 10/18/2020 2:24:52 PM
COVID>Brain:
Oct. 13, 2020
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF-barrier in human brain organoids
"We find that infected cells are apolipoprotein and ACE2 expressing cells of the choroid plexus epithelial barrier. Finally, we show that infection with SARS-CoV-2 damages the choroid plexus epithelium, leading to leakage across this important barrier that normally prevents entry of pathogens, immune cells and cytokines into cerebrospinal fluid and the brain."
https://www.sciencedirect.com/science/article...via%3Dihub
https://www.cell.com/cell-stem-cell/fulltext/...20)30495-1
Oct. 13, 2020
SARS-CoV-2 infects the brain choroid plexus and disrupts the blood-CSF-barrier in human brain organoids
"We find that infected cells are apolipoprotein and ACE2 expressing cells of the choroid plexus epithelial barrier. Finally, we show that infection with SARS-CoV-2 damages the choroid plexus epithelium, leading to leakage across this important barrier that normally prevents entry of pathogens, immune cells and cytokines into cerebrospinal fluid and the brain."
https://www.sciencedirect.com/science/article...via%3Dihub
https://www.cell.com/cell-stem-cell/fulltext/...20)30495-1
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