Thanks, Ohm. Here's something I found re Hunt
Post# of 148184
(Total Views: 515)
Posted On: 09/08/2020 7:00:10 AM
Thanks, Ohm.
Here's something I found re Huntington and CCR5, though I might be misunderstanding it: CCR5KO means CCR5 Knock Out -- the focus of the article:
"Of note, the five highest scoring canonical pathways each for CCR5WT-specific and CCR5WT/KO common gene sets all belonged in the categories of immune system and inflammation (Fig. 4A–J). Notably, two of the five canonical pathways affected by differential gene expression specific to CCR5WT explicitly implicated macrophages in gp120-associated neuronal injury and behavioral impairment (Fig. 4A and E). One pathway was specifically CCR5 signaling in macrophages. In contrast, CCR5KO-specific regulated pathways mapped to the nervous system, namely the γ-amino butyric acid (GABA) neurotransmission system and Huntington’s Disease (HD, Fig. 4K and N), to basic physiological mechanisms (Fig. 4M and O) and one inflammation-related pathway (Fig. 4L)."
This is https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370188/
Here's something I found re Huntington and CCR5, though I might be misunderstanding it: CCR5KO means CCR5 Knock Out -- the focus of the article:
"Of note, the five highest scoring canonical pathways each for CCR5WT-specific and CCR5WT/KO common gene sets all belonged in the categories of immune system and inflammation (Fig. 4A–J). Notably, two of the five canonical pathways affected by differential gene expression specific to CCR5WT explicitly implicated macrophages in gp120-associated neuronal injury and behavioral impairment (Fig. 4A and E). One pathway was specifically CCR5 signaling in macrophages. In contrast, CCR5KO-specific regulated pathways mapped to the nervous system, namely the γ-amino butyric acid (GABA) neurotransmission system and Huntington’s Disease (HD, Fig. 4K and N), to basic physiological mechanisms (Fig. 4M and O) and one inflammation-related pathway (Fig. 4L)."
This is https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370188/
(0)
(0)CytoDyn Inc (CYDY) Stock Research Links
Scroll down for more posts ▼