CCL5 is Rantes. Same protein. There are some gramm
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Posted On: 04/28/2020 5:08:52 AM
Re: chazzledazzle #30449
Quote:
CCL5 is Rantes. Same protein. There are some grammatical problems in the following translation, but Rantes/CCL5 is a protein involved in binding to CCR5 receptor. In my laymen’s terms (bc I’m a layman), it’s involved in allowing this Virus to attach and take over our immune system.
Neither CCL5 (chemokine) or CCR5 (receptor) has any role in the virus binding to the ACE2 receptor.
Quote:
The IL-6 cytokine we’ve been hearing about, while a very significant thing, isn’t as key to the Leronlimab effect
IL-6 is one of the keys, CCL5 binding to CCR5 upregulates IL-6 and IL-6 is the most potent cytokine for inflammation. The action of leronlimab blocking CCL5 it downregulates IL-6 keeping the cytokine storm at bay.
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