You're quite clearly correct to note that the tumor response is incredibly important. I'm sure that the reason that some (myself included) are very interested in the CTC count is because of CTC's potential use as a surrogate endpoint for accelerated approval. I know that tumor response is actually much more indicative of clinical benefit (typically defined as extended overall survival horizons or progression-free survival for oncology, for which surrogates are supposed to be an quicker to evaluate proxy), but I think the best chance for AA is through consistent, strong demonstration of an effect on the predominant surrogate endpoint. Thus, the more patients both in and out of the naïve protocol who show drastically reduced - even zero! - CTC counts, the better chance that I believe the company has of seeing not just BTD, but marketing approval.
Obviously, the fact that there is significant tumor response is fantastic news in and of itself, and should be celebrated for more than one reason! But it sounds like significant tumor shrinkage was only noted in NP's mother-in-law. I'm incredibly happy for her, but that also means that the absence of significant tumor shrinkage in patient 1 could highlight the potential importance of patient 2's CTC readings if the goal is simply to get this on the market and start helping people as quickly as possible.
Category: MarketsTotal Views: 113 By : EditorUpdated: 06-02-2024
Introduction to Key Market Insights
Investors and traders are preparing for a possibly wild trading day on June 3, 2024, which could be led by a series of economic data releases, followed by corporate earnings and some broader market trends. In this ultimate guide, we will explore the stocks to watch, economic flags, and other key market drivers ahead of this date.
Key Stocks to Watch
1. Medtronic, Inc (MDT)
Current Stock Price: $81.37
Medtronic might be one of the best picks in a... Continue Reading
Category: CryptoTotal Views: 136 By : EditorUpdated: 06-02-2024
Introduction to Meme Coins
The cryptocurrencies world is always full of surprises, and meme coins are here to stay that fascinate the investor and enthusiast in everyone. But behind the hype and speculative frenzy, a few meme coins are demonstrating genuine use-case and longevity. In this post, we will get an insight into a few of these projects: Shiba Shootout and Dogeverse which have their own exceptional utilities, staking rewards and community engagements.
The Origins of Meme Coins
... Continue Reading
Category: InvestingTotal Views: 141 By : EditorUpdated: 06-02-2024
Introduction: Investing in Emerging Technologies
As we advance further into 2024, one can realize that fresh trends are not only revolutionizing daily usage but investment portfolios as well. Here are some of the most promising technologies that might be of interest and might be worth the investment this year. From AI to quantum computing, these are great opportunities for development and future advancement.
Artificial Intelligence: The Vanguard of Innovation
Artificial Intelligence is ... Continue Reading
Category: InvestingTotal Views: 136 By : EditorUpdated: 06-02-2024
Introduction to Investing in Fintech Startups
Investing in fintech startups is full of opportunities and threats at the same time. Yes, the fintech industry is growing at a rapid pace due to factors such as innovation and technology improvement and people's need for better financial services through technology. Thus, as an investor it is important to comprehend the latest ecosystem, pinpoint the start-ups and predict the possible threats in order to make efficient decision making. I will ... Continue Reading
Introduction: Best Side Hustles
In the fast-paced world of today, the trend of a side hustle has become more relevant as a way to increase your income, explore new interests and reach your financial goals. The good news is, there are so many choices out there that your way to a side hustle that complements your skills and social life this year seems easier than ever. Freelancing, online business, part-time job — there is something for everyone.
Freelancing
The opposite of a 9 to 5... Continue Reading
Category: InvestingTotal Views: 181 By : EditorUpdated: 06-01-2024
Introduction to Alternative Investments
Speculating, or investing has been an interesting subject for a long time and many people get pleasure not only out of making money but also out of compounding or magnifying the wealth of money that they have worked so hard for. Equities and fixed-income products have been the conventional instruments of investment, however, the world of diversified investment instruments is vast and may potentially offer investment yields you never knew existed. But to... Continue Reading
Category: MarketsTotal Views: 178 By : EditorUpdated: 06-01-2024
Introduction: Revolutionizing Stock Predictions
The Stock Market has always been like a Pokemon full of surprises for investors, it has an ever-changing environment with a mix of different elements all attracting investors globally with its potential to financially gain. Historically, such predictions are based on historical performance, financial reports and expert analysis. But, This is where this all changed with the introduction of Artificial intelligence (AI) in the field that has taken ... Continue Reading
Category: StocksTotal Views: 218 By : EditorUpdated: 06-01-2024
Introduction to Green Stocks
In a world with an ever-growing focus on global sustainability, it is no surprise that green energy stocks are becoming more and more appetizing to the investor who is looking to invest in the environmental solution to produce a financial return. Here are the best green energy stocks to watch for 2024 — each chosen based on its methodology to green energy, commercial potential, and recent execution.
1. Brookfield Renewable Partners LP (BEP)
Current Pri... Continue Reading
Category: StocksTotal Views: 363 By : EditorUpdated: 06-01-2024
June 2024 - Top 10 Stocks to Watch
Although we are still more than two years away from June 2024, investors are closely watching the market for potential opportunities offering impressive returns or a substantial market resiliency. Selected for their market position, recent performance & growth.
1. Tradeweb Markets Inc (TW)
With a $24.15 billion market cap, Tradeweb Markets Inc (TW) is a stock to watch this month. Currently priced at $109.01, Tradeweb Markets Inc is a noteworthy sto... Continue Reading
Category: StocksTotal Views: 275 By : EditorUpdated: 06-01-2024
Company Overview
About Nikola Corporation Nikola Corporation trades on the Nasdaq under the ticker symbol NKLA and is a pioneer in industrial and automotive technologies. The trucks include hydrogen fuel cell and battery electric with the goal of changing the commercial transportation segment, and are all zero-emission vehicles. Nikola is a Nebraska-based company that protects the new era with an emphasis on sustainability and innovation in the trucking industry through environmentally friend... Continue Reading