That's interesting. And within that there's this l
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Posted On: 01/19/2019 3:21:49 PM
That's interesting. And within that there's this link:
http://fortune.com/longform/alzheimers-diseas...akthrough/
Long article about an ethnobotanist who has studied cultures with unusually high/low rates of Alzheimer's, ALS or other neurodegenerative diseases.
Summary:
- Ethnobotanist Paul Cox discovered that the Chamorro people on Guam were 100 times more susceptible to diseases like Alzheimer's, Parkinson's, etc.
- The Chamorro diet of Flying Foxes contained high levels of BMAA - a toxin found in the brains of Chamorro with neurodegenerative diseases but not found in healthy people. Residents have since hunted the bat into extinction and younger Chamorro who haven't consumed Flying Foxes don't have the same health problems as the older Chamorro.
- Cox believes that the toxin BMAA causes protein "misfolding that can trigger the death of neurons."
- Cox is now focused on L-Serine which is "an important [Astrocyte-derived] " neurotrophic factor in the CNS."
- Cox visited Ogimi in Japan which "advertises itself as the Village of Longevity; it has the most centenarians per capita ... The Ogimi people are getting three to four times the level of L-serine that Americans get in their average daily diet,” Cox said. “They have the highest L-serine content of any population that I’ve ever measured."
- "Cox has steered the focus of [his Wyoming-based] lab to L-serine, which he believes could significantly delay the onset of Alzheimer’s and the progress of its symptoms."
- “Here’s what we now think is astonishing about L-serine,” Cox said. “It appears to be neuroprotective against all possible protein misfolding. It basically turns on a system in our brains that looks for unfolded proteins and is quickly poised to act on them.”
http://fortune.com/longform/alzheimers-diseas...akthrough/
Long article about an ethnobotanist who has studied cultures with unusually high/low rates of Alzheimer's, ALS or other neurodegenerative diseases.
Summary:
- Ethnobotanist Paul Cox discovered that the Chamorro people on Guam were 100 times more susceptible to diseases like Alzheimer's, Parkinson's, etc.
- The Chamorro diet of Flying Foxes contained high levels of BMAA - a toxin found in the brains of Chamorro with neurodegenerative diseases but not found in healthy people. Residents have since hunted the bat into extinction and younger Chamorro who haven't consumed Flying Foxes don't have the same health problems as the older Chamorro.
- Cox believes that the toxin BMAA causes protein "misfolding that can trigger the death of neurons."
- Cox is now focused on L-Serine which is "an important [Astrocyte-derived] " neurotrophic factor in the CNS."
- Cox visited Ogimi in Japan which "advertises itself as the Village of Longevity; it has the most centenarians per capita ... The Ogimi people are getting three to four times the level of L-serine that Americans get in their average daily diet,” Cox said. “They have the highest L-serine content of any population that I’ve ever measured."
- "Cox has steered the focus of [his Wyoming-based] lab to L-serine, which he believes could significantly delay the onset of Alzheimer’s and the progress of its symptoms."
- “Here’s what we now think is astonishing about L-serine,” Cox said. “It appears to be neuroprotective against all possible protein misfolding. It basically turns on a system in our brains that looks for unfolded proteins and is quickly poised to act on them.”
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