SO tell me what is a SAFE/EFFECTIVE B-IBD drug wor

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SO tell me what is a SAFE/EFFECTIVE B-IBD drug worth up front? I'd say at least $200mm.
Pictures do tell a story.
Now throw in B-OM.....
$300mm upfront deal will send the market in to a frenzy.

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It makes sense to me. The size should be good with 5+ indications (OM,UP,UPS,UC, Crohn's). It's all about whether the deal closes. People with experience have said that it almost always does but other people were trotting out 50% stats regarding term sheet signed -> deal.

God, let it be $300M upfront.