Response to recent Drano post

Seems I need to clear up some issues for Drano and anyone else who read my posts today. Hopefully this will satisfy all involved and sorry for any lapse of memory or misunderstanding. As I noted to Drano in PM conversation, it has been well over a decade since I prescribed any antifungal due to change in practice venue and actually has probably been closer to two decades since I've done it routinely so my memory was a little fuzzy and I didn't feel the need to refresh it while trying to make what I thought was a simple side point. When I was trained (in the 1980's) we were often more limited in available drug forms to give and the vaginal troche (Mycelex if I recall from the time) was one of the only readily available ways to reach a higher concentration of drug to the involved site for oral candida infection than the commonly used oral antifungal rinses (of which several were available but also often not highly effective). It sounds strange and we always explained to the patient the logic behind its use for the more intractable infections but it often worked where the oral rinses would not. My simple point was that a "swish and spit" delivery is often difficult if not impossible for OM patients and for that reason other delivery methods might be more effective in the future. Pastilles/lozenges have become available in more recent years for oral administration in treatment of fungal infection, possibly an example of such off label uses of other forms of the drugs in years past.

I never suggested that any antifungal was used to treat oral mucositis (read the post carefully and you will see that). The antifungal was mentioned to note an "off label" use of a medication and a possibility of future change to delivery method of Brilacidin to target this limited/specific physiological site. I certainly do not know more than the scientists at IPIX and I am confident that they will maximize effectiveness of delivery.

Read Drano post 39588 12/4/17 and then search "can the flu shot give you the flu" and read the CDC information. A phd friend got the flu after receiving the flu shot so it must have been from the shot. Couldn't have been that he was already exposed and in development at the time of the shot, could it?

Not my intent to single anyone out here but I stand by all my earlier statements, as confusing and dated as they may have been. It is always important to do your own DD and reasoning before accepting anything you read on the internet.