The importance of the bacteria that live in the gut is just now beginning to be understood. One of the problems with taking antibiotics in pill form is that is kills off not only the bad disease-causing bacteria, but also the beneficial "good" bacteria that you need. For instance, some bacteria manufacture B vitamins in your gut, and the B vitamins are very important to health.
That's why, after you've taken antibiotics for an infection, it's important to go to a health food store or food coop or Whole Foods, and buy a really good brand of probiotics -- the good bacteria, which you take in pill form to replenish the good bacteria in your insides. The best ones are the ones in the refrigerated case, because they are fresh live bacteria.
The emerging practice of fecal transplants -- putting the good bacteria from a healthy person into a sick person -- have proven to be a great treatment for otherwise terrible conditions that are hard to treat, like c. difficile infections
http://www.webmd.com/digestive-disorders/clos...-colitis#1
There are also good bacteria that live on your skin. By virtue of living there, they prevent the BAD bacteria that you come in contact with from being able to colonize your skin and take over.
So, you can see that you don't want to kill off any more bacteria than you need to.
That's what is great about Brilacidin-UP via enema -- very, very little of the antibiotic gets into the bloodstream, so you're not killing off the bacteria anywhere except in that lower 12-14 inches of the colon. It doesn't kill off all the good bacteria everywhere else.
So, for skin conditions like acne and eczema etc. you'd want a topical cream, so that the medication goes right where it needs to, and doesn't kill off bacteria anywhere else.
And that's also why Mr. Ehrlich mentioned the capsule technology that can release medication at certain points in the intestinal tract -- so that it releases it where it's needed (and will continue to travel below that point) but not the part of the intestinal tract above where the medication starts getting dumped out.
Completing the safety tests successfully for one formulation (for instance, topical cream) will speed things up for other similar formulations because it's already been proven safe. But in general if you prove something is safe topically, it isn't necessary safe as an IV infusion or in pill form so those would have to have some safety trials. Going the other way, if it's safe as an IV then it should be safe topically. We already did the IV tests for Bril-ABSSSI so we should be able to move fast for other applications
That's why, after you've taken antibiotics for an infection, it's important to go to a health food store or food coop or Whole Foods, and buy a really good brand of probiotics -- the good bacteria, which you take in pill form to replenish the good bacteria in your insides. The best ones are the ones in the refrigerated case, because they are fresh live bacteria.
The emerging practice of fecal transplants -- putting the good bacteria from a healthy person into a sick person -- have proven to be a great treatment for otherwise terrible conditions that are hard to treat, like c. difficile infections
http://www.webmd.com/digestive-disorders/clos...-colitis#1
There are also good bacteria that live on your skin. By virtue of living there, they prevent the BAD bacteria that you come in contact with from being able to colonize your skin and take over.
So, you can see that you don't want to kill off any more bacteria than you need to.
That's what is great about Brilacidin-UP via enema -- very, very little of the antibiotic gets into the bloodstream, so you're not killing off the bacteria anywhere except in that lower 12-14 inches of the colon. It doesn't kill off all the good bacteria everywhere else.
So, for skin conditions like acne and eczema etc. you'd want a topical cream, so that the medication goes right where it needs to, and doesn't kill off bacteria anywhere else.
And that's also why Mr. Ehrlich mentioned the capsule technology that can release medication at certain points in the intestinal tract -- so that it releases it where it's needed (and will continue to travel below that point) but not the part of the intestinal tract above where the medication starts getting dumped out.
Completing the safety tests successfully for one formulation (for instance, topical cream) will speed things up for other similar formulations because it's already been proven safe. But in general if you prove something is safe topically, it isn't necessary safe as an IV infusion or in pill form so those would have to have some safety trials. Going the other way, if it's safe as an IV then it should be safe topically. We already did the IV tests for Bril-ABSSSI so we should be able to move fast for other applications
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