The side effects of other antibiotics used for the
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Posted On: 07/26/2017 4:13:21 PM
The side effects of other antibiotics used for the kind of severe infections (ABSSSI) we're talking about, are FAR, FAR worse than the side effects seen with Brilacidin. The bad side effects that PolyMedix observed were because they were using massive doses, orders of magnitude higher than what IPIX/CITX used in the first round of clinical trials.
The management has made it clear that the only reason we have not proceeded with the Bril-ABSSSI trial is the gigantic expense of such a trial -- about 30 million bucks if I remember correctly.
That's why it makes utter sense for the Brilacidin-UP and Brilacidin-OM trials to be done first -- they are, relatively speaking, cheap, fast, and easy (well, okay, I don't consider daily enemas to be "easy" for the patient, but for those running the clinical trial, it's a lot easier than having to get a patient in every day for an IV).
The management has made it clear that the only reason we have not proceeded with the Bril-ABSSSI trial is the gigantic expense of such a trial -- about 30 million bucks if I remember correctly.
That's why it makes utter sense for the Brilacidin-UP and Brilacidin-OM trials to be done first -- they are, relatively speaking, cheap, fast, and easy (well, okay, I don't consider daily enemas to be "easy" for the patient, but for those running the clinical trial, it's a lot easier than having to get a patient in every day for an IV).
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