jegfsu on YMB provided the answer I disagree wi
Post# of 30028
Posted On: 01/16/2015 11:58:02 AM
jegfsu on YMB provided the answer
I disagree with your logic completely. First of all, your math is incorrect at the outset. If there are 50 out of the 100 who actually have AD, then, with a sens. of 94%, there will be 47, not 46, who will test positive using Lympro.
But here's the deal- if big pharma tests those 100 initial patients with the inexpensive Lympro route, and 50 test positive with Lympro, those are the ones who wil be allowed further into the study- the other 50 won't matter. It doesn't matter to the company how many of the negatives are false negatives and actually have the disease. The test will have saved them big money with regard to further, more expensive testing. They can go and screen another completely different 100 person sample size with Lympro to get more patients in the study
I disagree with your logic completely. First of all, your math is incorrect at the outset. If there are 50 out of the 100 who actually have AD, then, with a sens. of 94%, there will be 47, not 46, who will test positive using Lympro.
But here's the deal- if big pharma tests those 100 initial patients with the inexpensive Lympro route, and 50 test positive with Lympro, those are the ones who wil be allowed further into the study- the other 50 won't matter. It doesn't matter to the company how many of the negatives are false negatives and actually have the disease. The test will have saved them big money with regard to further, more expensive testing. They can go and screen another completely different 100 person sample size with Lympro to get more patients in the study
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