MANF was discovered from the first of Amarantus' 8
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Astrocytes are glial cells in the brain that support neuroprotection, neurogenesis and synaptogenesis. PhenoGuard is the cell immortalization process developed by Company scientists to create immortal lines of astrocytes from various parts of the brain associated with neurodegenerative diseases. These immortal lines give the Company a competitive advantage in the search for undiscovered neurotrophic factors that address critically important biological pathways involved in human diseases.
The Company believes it can discover a stable of novel MANF-like proteins using its proprietary PhenoGuard platform technology. PhenoGuard was originally developed in the Neurotrophic Factors Group at the National Institute of Neurological Disorders and Stroke (NINDS) in Bethesda, Maryland.
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