I agree, he owes shareholders an explanation after

I agree, he owes shareholders an explanation after the lackluster presentation today. I imagine many will base their decision of whether to remain a shareholder on how he addresses their concerns over unmet expectations that were largely fueled by his blogs and comments over the last several weeks.

I've sent an email as I am sure many here have asking for an explanation.

That being said, I still maintain an long-term focus and I'm not going to jump off the roof over a snapshot of my investment valuation. This could snap back just as hard on positive news that we've been led to believe is forthcoming in the next few weeks. I'm not denying there has been a serious loss of credibility here. I'm just choosing to not let today's drop affect my overall attitude or the other parts of my life. I always have a plan B if plan A doesn't work out.

So far I've seen nothing that will alter my Plan A with AMBS as a great long-term investment. Those with shorter-term outlooks obviously feel differently. If anyone feels I'm a fool for having this attitude, I'm not offended by that. I've invested heavily here based on my own DD. But I always maintain the possibility it might not work out in the back of my mind. After all, this is a pre-revenue biotech and the investment risk will continue to be high until success in the market is realized.