Piramal Pharma Expands US Operations with $90 Million Investment

Piramal Pharma's Significant Investment in the US Market
Piramal Pharma Limited is making a powerful move by committing $90 million to expand its operations in the United States. This investment is part of a broader strategy to meet the growing demand for pharmaceuticals in the region and bolster local production capabilities. The investment includes crucial enhancements to two of its existing facilities, aimed at reinforcing the company’s commitment to US-based drug supply innovation driven by local demand.
Expanding Capabilities in Lexington and Riverview
The first of the two sites undergoing expansion is in Lexington, Kentucky. This facility specializes in producing sterile injectable drug products. The new expansion will add 24,000 square feet of manufacturing space, outfitting it with advanced commercial-scale capabilities designed to increase production efficiency. Key enhancements include the installation of a new filling line, two state-of-the-art lyophilizers, a special capping machine, and an external vial washer. With these upgrades, the Lexington facility is set to better support client needs, allowing for rapid scale-up of injectable medications.
Innovations in Riverview, Michigan
Meanwhile, the Riverview, Michigan facility will likewise see substantial improvements. Over its 50 years of operation, this site has built a reputation for excellence in developing active pharmaceutical ingredients (APIs) and high potency APIs (HPAPIs). The new expansion at Riverview will introduce commercial-scale capabilities for crafting payload-linkers, essential components in the production of bioconjugate drugs, which include targeted therapies such as antibody-drug conjugates (ADCs). The aim is for this enhanced suite to begin operations before the end of 2025, significantly boosting production capabilities in line with industry demands.
Strategic Rationale Behind the Expansions
Piramal Pharma's expansions are part of a strategic initiative to adapt to the evolving landscape of drug supply and manufacturing. CEO Peter DeYoung highlighted that these investments reflect a commitment to localize drug manufacturing while continuing to build on previous investments totaling $570 million in the US. This substantial commitment points to the US being the company's largest market, allowing Piramal to employ approximately 750 people domestically. The focus on expanding the capacities at these facilities aligns with customer preferences for onshore manufacturing options.
Benefits for Drug Development and Patients
This expansion is not just an operational upgrade; it also enhances the drug development timeline. Through its integrated ADC program branded as ADCelerate™, Piramal Pharma is positioned to expedite the transition from project initiation to production-ready GMP drug products within just 12 months without sacrificing quality. The integrated services ensure that patients gain quicker access to important treatments, minimizing the overall burden of disease.
About Piramal Pharma Limited
Piramal Pharma Limited operates as a leading player in the global pharmaceutical landscape, boasting a strong portfolio through 17 global development and manufacturing facilities. The company is comprised of various divisions—including Piramal Pharma Solutions, a top-tier contract development and manufacturing organization, and Piramal Critical Care, specializing in critical hospital generics. Such diversified operations allow Piramal to cater to numerous markets across over 100 countries, positioning itself favorably in a competitive industry. In addition, their partnership with Abbvie Therapeutics India has established Piramal as a significant player in the ophthalmology niche of the Indian pharmaceutical market.
Frequently Asked Questions
Why is Piramal Pharma investing $90 million in the US?
The investment aims to expand two existing facilities, enhancing their capacity to meet increasing demand and support local drug manufacturing.
What specific capabilities are being added at the Lexington facility?
The Lexington facility will gain commercial-scale manufacturing capabilities including a new filling line and advanced lyophilization technology for injectables.
What is the significance of the Riverview expansion?
The Riverview site will add commercial capabilities for payload-linker production, vital for developing advanced bioconjugate drugs including ADCs.
How does the ADCelerate™ program benefit drug development?
ADCelerate™ speeds up the development timeline, allowing projects to move from initiation to GMP production in just 12 months while maintaining high-quality standards.
What is Piramal Pharma's overall focus in the pharmaceutical market?
Piramal Pharma is committed to developing patient-centric solutions that reduce the burden of disease, showcasing its dedication to healthcare improvements globally.
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