Ottimo Pharma Achieves Major Funding Milestone for Cancer Research

Ottimo Pharma Raises Significant Funding for Innovative Cancer Therapies

Ottimo Pharma has successfully announced that it has raised over $140 million in a Series A financing round. This funding marks an important milestone for the company, aiming to accelerate its lead asset, Jankistomig, which is a first-in-class PD1/VEGFR2 bifunctional antibody. The financing will contribute significantly to further development in multiple solid tumor indications.

Leadership Changes to Drive Ottimo's Growth

The financing round was led by notable investors such as OrbiMed, Avoro Capital, and Samsara BioCapital, along with significant contributions from Medicxi, the company’s founding investor. This includes participation from respected firms like RTW Investments, Decheng Capital, and J.P. Morgan Life Sciences Private Capital. In alignment with these developments, the board of directors will be joined by industry veterans from these firms, ensuring a combination of expertise and innovation for Ottimo.

Strengthening of Research and Development

In addition to the substantial funding, Ottimo Pharma has made noteworthy changes within its leadership team. Under the guidance of CEO David Epstein, the company has appointed Rick Anderson as SVP Finance, Spencer Fisk as Chief Technical and Quality Officer, and Ling Zeng as General Counsel and EVP of Execution. Each of these leaders brings extensive experience from their previous roles at leading pharmaceutical firms where they contributed significantly to their companies' successes.

Innovating Cancer Treatment with Jankistomig

Ottimo's lead candidate, Jankistomig, represents a transformative approach in cancer treatment. This bifunctional antibody uniquely targets immune checkpoint inhibition as well as angiogenesis, positioning it as a dual pathway therapy. This leap in innovative design aims to create a more effective treatment option for patients suffering from various solid tumors.

Future Development Plans

Currently, OTTIMO is actively engaged in IND-enabling studies for Jankistomig, with the intent to file an Investigational New Drug (IND) application by late 2025. The company anticipates the bifunctional antibody could play a pivotal role in addressing a global oncology market worth over $50 billion. Their strategic development and thorough understanding of tumor pathology lay the groundwork for significant advancements in treatment.

Comments from Leadership

In his statement, David Epstein expressed excitement about the implications of this funding, highlighting the significant potential it holds for extending the lives of cancer patients. With honest gratitude towards their investors, he stated, "This successful financing round solidifies our efforts toward bringing Jankistomig to the clinical stage. We are thrilled to have a proven leadership team ready to guide Ottimo through this important phase of growth."

Vision for the Future

In a separate comment, Peter Thompson from OrbiMed praised Ottimo's distinctive approach in the oncology field and the vast experience that the team brings. He noted how they are looking forward to playing a role in developing new therapeutic treatments that could significantly enhance patient outcomes.

Acknowledging Remarkable Progress

Francesco De Rubertis, Co-Founder of Medicxi, also chimed in to acknowledge Ottimo's substantial progress with Jankistomig. His insight as both investor and board member illustrates the optimistic outlook on Ottimo's journey ahead with new top-tier investors onboard.

About Ottimo Pharma

Founded in 2020, Ottimo Pharma is driven by a mission to transform how cancer is treated through pioneering therapies. Their flagship development, Jankistomig, epitomizes innovation, focusing on dual-pathway treatments that seek to improve patient outcomes significantly. As Ottimo prepares for its first IND filing, they continue to build a promising future in the biotech space.

Frequently Asked Questions

What is Ottimo Pharma's recent funding achievement?

Ottimo Pharma has raised over $140 million in a Series A financing round aimed at advancing its lead oncology therapy, Jankistomig.

Who are the main investors in Ottimo Pharma's funding round?

The funding was predominantly led by OrbiMed, Avoro Capital, and Samsara BioCapital, alongside contributions from Medicxi and other distinguished investors.

What is Jankistomig?

Jankistomig is Ottimo's lead candidate, a unique PD1/VEGFR2 bifunctional antibody designed to treat multiple solid tumor types.

When is Ottimo Pharma planning to file for IND?

Ottimo Pharma aims to file for an Investigational New Drug (IND) application in late 2025 for Jankistomig.

What is the vision of Ottimo Pharma?

Ottimo Pharma is focused on developing innovative cancer therapies that enhance patient outcomes and reduce overall healthcare burdens.

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