Ossium Health Partners with BARDA for Emergency Response Advancements
Ossium Health Partners with BARDA for Emergency Response Advancements
Ossium Health, a pioneering bioengineering firm, is making waves with its innovative bone marrow bank aimed at efficiently processing and deploying stem cell-based therapies during national emergencies. The company has recently entered into a significant contract with the Biomedical Advanced Research and Development Authority (BARDA), an integral part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services. This partnership focuses on enhancing the company's ready-to-use bone marrow supply in preparation for radiological and nuclear emergencies.
Contract Details and Funding Potential
The initial funding for this contract stands at $21 million for its base period, with a remarkable potential total value of $125 million anticipated over a duration of five years. This funding is crucial for Ossium Health as it gears up to accelerate the processing of its proprietary Hematopoietic Progenitor Cell (HPC) Marrow product. The project will also involve numerous clinical studies to ascertain the safety and efficacy of the treatments being developed. Furthermore, the collaboration aims to expand Ossium's existing network of bone marrow banks across the United States, thus fortifying national preparedness against public health emergencies.
Importance of Bone Marrow in Crisis Situations
In catastrophic scenarios, particularly in the case of nuclear or radiological incidents, survivors exposed to significant radiation levels risk developing Acute Radiation Syndrome (ARS). This severe condition arises from the critical destruction of bone marrow. Without timely treatment, ARS can prove to be fatal; however, with a bone marrow transplant (BMT), affected individuals can hope for recovery. Ossium Health's groundbreaking approach to bone marrow banking was initially designed to aid blood cancer sufferers requiring transplants. Now, it represents a proactive solution for potential public health crises, supplying a robust and quickly retrievable stockpile of bone marrow from deceased donors. This strategic planning mitigates logistical issues often encountered with living volunteer donors during emergencies.
Statement from the CEO
CEO and Co-Founder, Kevin Caldwell, expressed his enthusiasm regarding this new venture. Caldwell emphasized, "Our method provides a vital solution for safeguarding public health. The ability to swiftly deliver bone marrow units in the face of a radiological or nuclear disaster could be lifesaving and fundamentally change our emergency response protocols. We are excited about this partnership enhancing our national preparedness efforts."
Enhancing Clinical Outcomes with Innovative Solutions
The distinctive HPC, Marrow product is harvested from recently deceased organ donors, meticulously processed, HLA-typed, and then cryopreserved for future applications. This innovative method not only promotes expedited responses during emergencies but is also beneficial for oncology patients in need of bone marrow transplants. Current participants enrolled in Ossium’s clinical study (PRESERVE I) benefit from the unique ability to receive transplants at optimal times and dosages, ensuring maximum therapeutic effectiveness.
Federal Support and Future Directions
This project receives federal support through the Department of Health and Human Services, particularly under BARDA’s auspices. Such backing underscores the importance of the initiative in preparing for health crises that could arise in the future.
About Ossium Health
Ossium Health stands at the forefront of bioengineering, utilizing its exclusive organ donor bone marrow banking system to craft stem cell therapies aimed at treating critical hematologic disorders, combating organ transplant rejection, and addressing musculoskeletal defects. Established in 2016, Ossium is steered by leaders Kevin Caldwell, who serves as CEO, President, and Co-Founder, alongside Erik Woods, Chief Science Officer and Executive Vice President. Their state-of-the-art manufacturing facility is FDA-registered, and the laboratory adheres to Clinical Laboratory Improvement Amendments (CLIA) standards. For more insights on Ossium Health's legacy and ongoing projects, visit their official website.
Frequently Asked Questions
What is Ossium Health's recent advancement?
Ossium Health has secured a contract with BARDA to enhance its bone marrow bank for national emergencies, specifically aimed at improving readiness for radiological and nuclear incidents.
How much funding was acquired for the BARDA contract?
The contract begins with $21 million in funding, with the possibility of reaching up to $125 million over five years.
What is the significance of the Hematopoietic Progenitor Cell (HPC) Marrow product?
This product is crucial for providing bone marrow transplants and is designed for rapid deployment during emergency situations.
Who leads Ossium Health?
Ossium Health is led by Kevin Caldwell as CEO and Erik Woods as Chief Science Officer.
How does Ossium Health's strategy mitigate risks during emergencies?
The company maintains a large inventory of cryopreserved bone marrow, enabling quick responses without depending solely on living donors during crises.
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