OMass Therapeutics Strengthens Team and Advances MC2 Candidate
OMass Therapeutics Strengthens Team and Advances MC2 Candidate
OMass Therapeutics, a pioneering biotechnology company, is making strides in its mission to develop innovative medicines targeting highly validated ecosystems. Recently, the company announced key appointments in the United States and the United Kingdom to bolster its development team while nominating its first clinical candidate aimed at the melanocortin-2 (MC2) receptor.
Significant Progress in Development Pipeline
Over the past year, OMass has dedicated itself to advancing its proprietary pipeline, now selecting its first clinical candidate specifically targeting the MC2 receptor, which is known to interact with the adrenocorticotropic hormone (ACTH). This strategic choice is designed to enhance receptor residency time, providing resilience against competition from the body's own ligand. Consequently, this innovation is poised to offer treatments for patients suffering from conditions such as congenital adrenal hyperplasia and Cushing’s syndrome, which are associated with ACTH excess.
The Need for Innovative Solutions
ACTH-related conditions can significantly impair patients' quality of life, making effective treatment options vital. The extended receptor residence time sought by OMass may be crucial in ensuring consistent efficacy even when ACTH levels fluctuate—offering a new lease of life to those managing these challenging health conditions.
Expanding Expertise: New Appointments
In a strategic move to support its ambitious pipeline, OMass has expanded its development team. With these recent appointments, the company enhances its expertise in clinical development and manufacturing processes.
Introducing the New Team Members
Dr. Steve Griffen has joined OMass as the Vice President of Clinical Development. With over 25 years of experience in clinical research, Steve brings invaluable knowledge from prior roles, including Vice President of Clinical Development at MBX Biosciences and Medical Lead at Sanofi. His extensive background in endocrinology will fuel OMass’s efforts to push the MC2 program into clinical stages.
Following Steve is Angela Hecyk, who has been appointed as the Director of Clinical Operations. Angela contributes more than 16 years of clinical research experience, having worked on programs leading to several FDA approvals. Her proactive approach and understanding of clinical trials, particularly in rare conditions, will help steer OMass towards its goals.
Additionally, Stuart Hadley has been designated as Senior Director of Chemistry Manufacture and Controls (CMC). Stuart arrives with over 25 years of experience in drug development and operations—a critical asset in ensuring smooth CMC processes as OMass prepares its candidate for the clinic.
Leadership Insights: Vision for the Future
Ros Deegan, Chief Executive Officer of OMass Therapeutics, shared her enthusiasm about the company's direction. She stated, "The nomination of our first clinical candidate marks an essential milestone for us. Welcoming Steve, Angela, and Stuart into our team adds substantial expertise that will be vital as we advance our MC2 program to clinical testing."
Dr. Steve Griffen echoed Ros's sentiments, expressing his excitement at joining OMass during such a transformative phase. He looks forward to collaborating with his new colleagues to propel the innovative pipeline forward.
About OMass Therapeutics
OMass Therapeutics specializes in discovering groundbreaking medicines against well-validated target ecosystems. The company's novel OdyssION™ drug discovery platform integrates next-generation native mass spectrometry with state-of-the-art biochemistry and custom chemistry. This versatile approach enables OMass to explore drug targets comprehensively while maintaining fidelity to the cell's ecosystem.
Targeting rare diseases and immunological conditions, the company is particularly focused on developing its best-in-class MC2 receptor antagonist aimed at treating Congenital Adrenal Hyperplasia and Cushing’s Syndrome. With over $160M raised from a diverse group of international investors, including Syncona and Oxford Science Enterprises, OMass is positioned to lead in the biopharmaceutical industry.
Frequently Asked Questions
What is the main focus of OMass Therapeutics?
OMass Therapeutics focuses on discovering and developing medicines targeting validated ecosystems, particularly in relation to membrane proteins and intracellular complexes.
What recent developments has the company announced?
The company has appointed key members to its development team and nominated its first clinical candidate targeting the MC2 receptor, crucial for treating ACTH-related conditions.
Who are the new appointments in the development team?
Dr. Steve Griffen is the new Vice President of Clinical Development, Angela Hecyk is the Director of Clinical Operations, and Stuart Hadley is the Senior Director of Chemistry Manufacture and Controls.
What challenges does OMass aim to address with its new candidate?
OMass aims to address efficacy loss in patients suffering from ACTH excess by providing a treatment that resists endogenous ligand competition and maintains receptor activity over time.
How is OMass supported financially?
OMass has successfully raised over $160M from top-tier international investors, enabling it to enhance its drug development efforts and advance its pipeline.
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