Oculis Welcomes Leading Experts as Chief Medical Advisors

Oculis Strengthens Leadership with Expert Appointments

Oculis Holding AG (NASDAQ: OCS), based in Switzerland, is making significant strides in ophthalmological and neuro-ophthalmological innovation. The company has recently announced the appointment of two distinguished experts, Mark Kupersmith, M.D., and Sebastian Wolf, M.D., Ph.D., as Chief Medical Advisors. These appointments signify a pivotal shift as Oculis aims to enhance its research and treatment capabilities in key areas that affect many patients.

Welcoming Dr. Mark Kupersmith

Dr. Mark Kupersmith takes on the role of Chief Medical Advisor for Neuro-Ophthalmology. His extensive background in both neurology and ophthalmology spans over 40 years, making him a respected figure in the field. With the successful results from the Phase 2 ACUITY trial of Privosegtor (OCS-05) for acute optic neuritis, Dr. Kupersmith’s expertise is expected to play an essential role in expanding Oculis' offerings in neuro-ophthalmology.

Impact of Privosegtor (OCS-05)

The results from the ACUITY trial were promising, showing potential improvements in visual function. This trial marks a critical development for treatments focused on preserving nerve cells and addressing neuro-protection. Dr. Kupersmith is motivated to leverage this promising asset, paving the way for groundbreaking therapies in neuro-ophthalmic disorders.

Introducing Dr. Sebastian Wolf

Joining Dr. Kupersmith is Dr. Sebastian Wolf, who will serve as Chief Medical Advisor for Ophthalmology. Dr. Wolf has an impressive background with specialties in retina and imaging, gained through decades of clinical experience. His recent engagements with Oculis have involved pivotal clinical trials, including the Phase 3 DIAMOND trials for OCS-01 eye drops aimed at treating diabetic macular edema.

Focus on Diabetic Macular Edema

The DIAMOND trials' completion opens a new chapter for Oculis as they prepare for topline results expected soon. Dr. Wolf's leadership promises to enhance the precision and quality of these initiatives, laying groundwork for submitting a New Drug Application (NDA) later.

Leadership Statements on New Appointments

Riad Sherif, M.D., Chief Executive Officer of Oculis, expressed enthusiasm about the appointments, stating how Dr. Kupersmith and Dr. Wolf's contributions align with the company's mission. Their extensive knowledge and prior successes are seen as invaluable to driving Oculis into its next phase as a leader in ophthalmology and neuro-ophthalmology.

Arshad Khanani, M.D., a member of Oculis' Board of Directors, complemented these sentiments by emphasizing that the new advisors bring unparalleled insight into treating optic nerve and retinal disorders, which remain significant challenges in patient care.

Profiles of the New Advisors

Dr. Mark Kupersmith's Credentials

Dr. Kupersmith is not just a practitioner; he has been a pioneer in neuro-ophthalmological research. His work includes leadership in clinical trials addressing optic neuritis. Throughout his career, he authored over 280 peer-reviewed publications and conducted numerous studies internationally. These experiences will be crucial in guiding Oculis’ evolving research landscape.

Dr. Sebastian Wolf's Academic Background

Dr. Wolf, with a Ph.D. in biotechnical engineering, combines both clinical and research excellence. His role at the Bern Photographic Reading Center and contributions to pivotal studies place him at the center of innovative vision therapies. With over 400 publications to his name, Dr. Wolf’s insights into retina-focused therapies will help guide Oculis through future clinical challenges.

About Oculis

Oculis operates globally, focusing on innovations to meet unmet medical needs in the ophthalmic sector. Their leading pipeline includes OCS-01, which targets diabetic macular edema, and Privosegtor (OCS-05), promising neuroprotective potential for acute optic neuritis. With a dedicated management team and ongoing projects, the company is positioned for significant growth in personalized medicine and advanced treatments.

Frequently Asked Questions

What are the roles of Dr. Kupersmith and Dr. Wolf at Oculis?

Dr. Kupersmith serves as Chief Medical Advisor for Neuro-Ophthalmology, and Dr. Wolf is Chief Medical Advisor for Ophthalmology.

What is the significance of the ACUITY trial results?

The ACUITY trial results are significant as they show improvements in visual function and support the potential for Privosegtor (OCS-05) as a treatment for acute optic neuritis.

When is Oculis expecting results from the DIAMOND trials?

Topline results from the DIAMOND trials are expected soon, with plans for a New Drug Application filing in the later half of the year.

What qualifications do Dr. Kupersmith and Dr. Wolf have?

Dr. Kupersmith brings over 40 years of research and clinical experience, while Dr. Wolf has a strong academic background and extensive involvement in significant ophthalmic research projects.

How does Oculis aim to meet patient needs?

Oculis focuses on developing innovative therapies that address significant unmet medical needs in ophthalmic and neuro-ophthalmic conditions, emphasizing advanced clinical research and patient-centered solutions.

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