Oculis Showcases Innovative Therapies in Ophthalmology Events

Spotlighting Oculis Innovations in Ophthalmology

Oculis Holding AG (Nasdaq: OCS), a pioneering biopharmaceutical company, is dedicated to creating cutting-edge treatments for ophthalmic and neuro-ophthalmic diseases. The company is highlighting its promising late-stage pipeline at key events focused on eye health, including Eyecelerator and the American Academy of Ophthalmology (AAO) Annual Meeting.

Late-Stage Pipeline Developments

During the Eyecelerator event, Oculis will have its Chief Executive Officer, Riad Sherif, MD, present exciting updates on new advancements. Notable highlights will include the planned initiation of registrational trials for Privosegtor aimed at treating acute optic neuritis and non-arteritic anterior ischemic optic neuropathy. This follows a productive discussion with the U.S. Food and Drug Administration (FDA) and showcases Oculis' commitment to developing breakthrough therapies.

Updates on Oculis Drug Candidates

In addition, attendees can expect insights into the ongoing Phase 3 DIAMOND program, which is evaluating OCS-01 eye drops for diabetic macular edema (DME), with topline results anticipated to be released in the near future. Furthermore, Oculis will provide further information about the upcoming PREDICT-1 registrational trial, exploring a genotype-based strategy for Licaminlimab in treating dry eye disease, set to commence soon.

Participation at AAO Annual Meeting

Oculis is also gearing up for significant involvement in the AAO Annual Meeting, where the company will engage in various collaborative platforms. The Innovate Retina event will feature a panel discussion with Arshad M. Khanani, MD, MS, FASRS, from Oculis’ Retina Scientific Advisory Board. He will discuss the revolutionary implications of eye drops like OCS-01 in transforming treatment approaches for DME.

Event Details

Here are the essential details of Oculis' upcoming presentations:

• Eyecelerator @ AAO 2025: Corporate presentation led by Riad Sherif on October 16, 2025, at 1:15 PM ET, at the Orange County Convention Center.
• Innovate Retina: Panel discussion by Arshad M. Khanani on October 16, 2025, at 5:25 PM ET, at Hilton.
• SAIVO: Scheduled for October 17, 2025, at 6:00 PM ET, at Hotel Landy.
• COPhy Satellite Symposium: Happening October 17, 2025, at 6:30 PM ET, at Hyatt Regency.
• AAO Annual Meeting: From October 18-20, 2025, at the Orange County Convention Center (booth 1353).

Advancements in Therapies

Privosegtor, one of Oculis’ pivotal drug candidates, is a novel small molecule that shows promise as a neuroprotective treatment for both acute optic neuritis and non-arteritic anterior ischemic optic neuropathy. Results from the Phase 2 ACUITY trial indicate that Privosegtor demonstrates potential neuroprotective properties by preserving retinal structure and improving vision after optic neuritis events. It's crucial to note that this investigational drug has received Orphan Drug designation from both the FDA and EMA.

Understanding Acute Optic Neuritis

Acute Optic Neuritis (AON) presents a significant challenge, characterized by the inflammation of the optic nerve, potentially leading to long-lasting visual impairment. It's an area where medical innovation is sorely needed, as there currently is no accepted neuroprotective therapy to curb vision loss after acute episodes.

Importance of Non-Invasive Treatments

OCS-01 eye drops, developed through Oculis' proprietary OPTIREACH technology, offer a promising non-invasive treatment option for diabetic macular edema. This development represents a shift in current treatment paradigms by providing a more accessible method than traditional invasive therapies. With an estimated 37 million people afflicted worldwide, the potential impact of OCS-01 could be transformative for individuals experiencing DME.

Oculis is strongly positioned to capture this significant market need with its innovative product pipeline. With a commitment to addressing critical unmet medical needs in the realm of ophthalmic health, the company looks ahead to advancing its clinical studies.

Frequently Asked Questions

What is Oculis focusing on at the Eyecelerator event?

Oculis will highlight its late-stage pipeline, including updates on Privosegtor and OCS-01 eye drops aimed at treating serious ophthalmic conditions.

What are the implications of Privosegtor's research?

Privosegtor has shown potential as a neuroprotective therapy, with promising results in clinical trials for treating acute optic neuritis.

How is Oculis addressing diabetic macular edema?

Oculis is developing OCS-01, a high-concentration dexamethasone eye drop designed to provide a non-invasive treatment alternative for diabetic macular edema.

Who is Arshad M. Khanani, and what will he discuss?

Arshad M. Khanani is a prominent ophthalmologist who will address the future role of eye drops in treating diabetic macular edema during the Innovate Retina panel.

What makes Oculis unique in the biopharmaceutical industry?

Oculis stands out for its commitment to innovating treatments for eye diseases with significant unmet needs, aiming to improve patient outcomes through advanced therapies.

About The Author

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