NuCana PLC Unveils Robust Financial Performance and Progress
NuCana Reports Positive Developments in Cancer Treatments
EDINBURGH, United Kingdom—In an update to investors, NuCana plc (NASDAQ: NCNA) shared exciting progress regarding its cancer therapies, NUC-7738 and NUC-3373, along with its financial outcomes for the third quarter of the year.
Encouraging Clinical Data Released
NuCana has recently presented compelling Phase 2 data on NUC-7738, demonstrating significant effects on gene expression in cancer cells. At a recent medical congress, the results highlighted a 75% control rate in resistant melanoma patients treated with NUC-7738 and pembrolizumab. A patient with prior treatment failures saw notable reductions in tumor size, showcasing the therapy's promise.
In addition, the Phase 1b/2 study of NUC-3373 indicated a potential to enhance immune response when combined with pembrolizumab or docetaxel, showing impressive results in tumor size reduction for some patients.
Financial Highlights for Q3 2024
As of September 30, 2024, NuCana reported cash and cash equivalents of £11.4 million, slightly down from prior quarters. The primary driver behind this decrease was operating expenditures, which were partially mitigated by successful capital raising efforts amounting to around £4.7 million via their at-the-market (ATM) program.
Net Loss and Financial Position
NuCana recorded a net loss of £4.5 million for Q3 2024, an improvement compared to a £6.7 million loss in the same period last year. Analysts noted that the adjusted loss per share was recorded at £0.07, down from £0.13 a year earlier, reflecting operational efficiencies.
Upcoming Milestones for 2025
NuCana has laid out a series of anticipated milestones set for 2025, indicating an expansion and further clinical trials for both NUC-7738 and NUC-3373. Key activities include launching expanded studies and seeking regulatory feedback for pivotal study designs aimed at attaining approval for their therapies.
Ongoing Commitment to Innovation
The leadership at NuCana, led by CEO Hugh S. Griffith, remains committed to advancing treatment options for cancer patients with continuous innovations in the biopharmaceutical space. They aim to alleviate the existing limitations faced by conventional chemotherapy agents through their ProTide technology.
About NuCana
NuCana PLC is on a mission to revolutionize cancer treatment. By applying its unique ProTide technology, NuCana transforms widely-used chemotherapy drugs into more effective treatments with improved tolerance profiles. Their candidate drugs, NUC-3373 and NUC-7738, are designed to maximize anti-cancer efficacy while minimizing side effects for patients.
Frequently Asked Questions
What is NuCana's focus in its development programs?
NuCana is dedicated to enhancing cancer treatment outcomes through innovative therapies, specifically focusing on its lead candidates NUC-3373 and NUC-7738.
How did NuCana perform financially in the last quarter?
NuCana reported a net loss of £4.5 million for Q3 2024, representing an improvement from the previous year, with cash holdings at £11.4 million.
What recent clinical data did NuCana present?
NuCana presented Phase 2 data demonstrating significant tumor shrinking and control in patients treated with NUC-7738 alongside pembrolizumab.
What are the next steps for NuCana's lead drug candidates?
NuCana plans to expand clinical trials for NUC-7738 and NUC-3373 in 2025 and seeks regulatory guidance for pivotal studies.
Who is leading NuCana?
Hugh S. Griffith is the Founder and CEO of NuCana, overseeing the strategic direction of the company and its innovative projects.
For more information, please contact:
NuCana plc
Hugh S. Griffith
Chief Executive Officer
+44 131-357-1111
info@nucana.com
ICR Westwicke
Chris Brinzey
+1 339-970-2843
chris.brinzey@westwicke.com
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