Northwest Biotherapeutics Expands Operations with Advent Acquisition

Northwest Biotherapeutics Announces Agreement to Acquire Advent BioServices Ltd

Northwest Biotherapeutics, Inc. (OTCQB: NWBO), a pioneering biotechnology firm dedicated to developing innovative DCVax® personalized immune therapies, has taken a significant step forward by entering into an acquisition agreement with Advent BioServices Ltd. This strategic move promises to enhance the Company’s operations by adopting a more integrated approach to its manufacturing and product development efforts.

Details of the Acquisition

The transaction will see Northwest Biotherapeutics acquiring Advent BioServices from its owner, Toucan Holdings LLC. The expectation is that the acquisition will close once specified legal conditions have been met. Upon completion, Advent will become a wholly owned subsidiary of Northwest Biotherapeutics, leading to a seamless integration of their operations.

This acquisition not only consolidates physical assets but also aims to streamline the Company's operational capabilities. Northwest Biotherapeutics will inherit Advent's extensive cryostorage facilities and various essential equipment acquired over the years. Additionally, around 19 million shares of NWBO that were earlier issued to Advent for contract services will revert to the Company, including 13.5 million shares and 5.5 million options.

Strategic Implications for Future Growth

Northwest Biotherapeutics has been collaborating closely with Advent on strategic planning to merge the operations of their London and Sawston GMP facilities. This consolidation aims to prioritize manufacturing ramp-up in Sawston, especially after intensive product and process development efforts geared towards their Marketing Authorization Application (MAA) and the DCVax®-Direct program have reached significant milestones.

The acquisition is structured to include payments over a period of two years, commencing 90 days after the agreement. This financial arrangement involves an initial payment of £1.4 million, in addition to settling the net accounts payable owed from Northwest Biotherapeutics to Advent for services rendered. These financial details have been shared in the Company's recent public filings.

Leadership Perspective

Linda Powers, the CEO of Northwest Biotherapeutics, expressed enthusiasm regarding the acquisition, stating, "This is an exciting day for the Company, entering into an agreement to bring our manufacturing and product development operations in-house. By integrating our teams and processes, we can increase our efficiency and better prepare for a potential substantial scale-up of our production capacity." This vision reflects the Company’s commitment to enhancing its operational footprint and advancing cancer treatment innovations.

About Northwest Biotherapeutics

Northwest Biotherapeutics specializes in creating personalized immunotherapy treatments, aiming to deliver more effective cancer therapies without the adverse side effects often associated with traditional chemotherapy. The Company’s primary focus revolves around its DCVax® platform technology, which encompasses dendritic cell-based vaccines.

The lead program, DCVax®-L, has undergone rigorous testing, completing a phase III trial involving 331 patients diagnosed with glioblastoma (GBM), recognized as one of the most formidable types of primary brain cancer. The results have been effectively communicated through scientific platforms, including publications in respected journals, and the Company is currently awaiting MAA review for commercial approval in the UK. Additionally, Northwest Biotherapeutics is advancing its DCVax®-Direct product for treating inoperable solid tumors, having completed phase I trials and gearing up for phase II this year.

Frequently Asked Questions

What prompted Northwest Biotherapeutics to acquire Advent BioServices?

The acquisition aims to integrate and enhance Northwest Biotherapeutics' manufacturing and development capabilities, thereby improving overall operational efficiency.

What assets will Northwest Biotherapeutics acquire from Advent BioServices?

The Company will receive all of Advent's fixed assets, including cryostorage facilities and equipment, along with securities that revert back to Northwest Biotherapeutics.

What is the anticipated impact of this acquisition on future operations?

This merger is expected to streamline operations, promote manufacturing synergy, and prepare the Company for significant business scaling.

How is the acquisition payment structured?

Payments for the acquisition are set to occur in installments over two years, starting 90 days post-agreement, which includes an initial £1.4 million payment.

What innovative therapies is Northwest Biotherapeutics developing?

Northwest Biotherapeutics is focused on its DCVax® platform, particularly aimed at glioblastoma and inoperable solid tumors, utilizing personalized immunotherapy approaches.

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