N2OFF's MitoCareX Merger: Catalyzing Innovation in Cancer Therapy

N2OFF's Strategic Merger with MitoCareX Bio Ltd

In a significant development, N2OFF, Inc. (NASDAQ: NITO), a leading cleantech company, has successfully completed its merger with MitoCareX Bio Ltd. This merger marks a pivotal moment in N2OFF's journey, expanding its focus towards innovative cancer therapies, particularly for challenging cases such as pancreatic and lung cancers.

The Vision Behind MitoCareX

MitoCareX is at the forefront of biotechnology, dedicated to discovering revolutionary drugs aimed at tackling some of the most resistant forms of cancer. Their approach is centered around the mitochondrial SLC25 protein family, which plays a crucial role in cellular metabolism. MitoCareX's proprietary tool, MITOLINE™, is a groundbreaking algorithm developed for advanced 3D modeling of these proteins, which facilitates the identification of promising anti-cancer compounds.

Innovative Approach to Cancer Treatment

With an advanced in-vitro screening system, MitoCareX not only discovers small molecules with potential anti-cancer properties but also validates their efficacy. This dual capability positions MitoCareX as a trailblazer in the quest for effective cancer therapies, harnessing technology to streamline drug discovery and development processes.

Market Potential and Future Growth

The cancer therapeutics market is on an upward trajectory, projected to grow from an estimated $211.02 billion in 2025 to a staggering $378.62 billion by 2032. This growth represents a compound annual growth rate (CAGR) of 8.7%, underscoring the increasing demand for innovative treatment options. N2OFF and MitoCareX are strategically positioned to leverage this market expansion, providing cutting-edge therapies that address unmet medical needs.

The Acquisition Details

The acquisition, finalized on October 20, 2025, involved an investment of $700,000 by N2OFF for MitoCareX's ordinary shares. This strategic transaction included an exchange of stock that effectively resulted in MitoCareX becoming a wholly-owned subsidiary of N2OFF. Additionally, the terms include a commitment from N2OFF to support MitoCareX's operations financially during the initial two-year post-acquisition period.

Leadership and Strategic Guidance

Mr. Amitay Weiss, chairman of the board of N2OFF, brings his expertise to this venture, also serving on the board of SciSparc Ltd (NASDAQ: SPRC). This interconnected leadership may foster synergistic benefits, enhancing the prospects for both companies. Furthermore, Ms. Liat Sidi, an active member of N2OFF’s board, is also associated with SciSparc, creating a robust collaborative framework.

Broader Impact and Responsibility

N2OFF isn’t solely concentrated on cancer therapeutics. The company continues to invest in renewable energy assets across Europe, focusing on solar projects. Moreover, N2OFF maintains a substantial share in Save Foods Ltd., which emphasizes pathogen control and preventive treatments in the agriculture sector. These ventures illustrate N2OFF's commitment to sustainable and impactful solutions across different industries.

Conclusion: A Focused Future for N2OFF

The merger between N2OFF and MitoCareX is expected to accelerate advancements in cancer therapeutics, offering hope for patients battling particularly tough cancers. With strong leadership, innovative technology, and a solid market strategy, N2OFF is poised to make significant contributions to both the biotech and renewable energy sectors moving forward.

Frequently Asked Questions

What is the main focus of N2OFF following the merger with MitoCareX?

N2OFF will focus primarily on developing innovative cancer therapies targeting hard-to-treat cancers, specifically leveraging advancements in mitochondrial protein research.

How is MitoCareX contributing to cancer treatment?

MitoCareX utilizes its proprietary MITOLINE™ algorithm to discover and validate anti-cancer molecules, contributing significantly to the field of biotechnology.

What are the financial implications of this merger for N2OFF?

The merger solidifies N2OFF's position in the cancer therapeutics market, promising potential returns from both the acquisition and future funding milestones defined in their agreement.

What types of cancers are targeted by MitoCareX's research?

MitoCareX focuses on challenging cancers, particularly pancreatic and lung cancers, through innovative therapeutic approaches.

What other investments does N2OFF have apart from MitoCareX?

N2OFF is actively investing in solar energy projects across Europe and holds a significant stake in Save Foods Ltd., which addresses pathogen contamination in agricultural products.

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