Monod Bio Unveils Innovative CRP Biosensor on NovoLISA Platform
Monod Bio Introduces NovoLISA Platform
Monod Bio, a pioneering life sciences company, has unveiled its latest innovation, the NovoLISA platform, designed specifically for research and diagnostics. This groundbreaking platform is a rapid, single-step biosensor assay that promises to deliver test results in just 15 minutes, significantly reducing the turnaround time compared to traditional methods like the ELISA assay. The platform's name, NovoLISA, reflects its purpose: "de Novo protein-Linked Instantaneous Solution-based Assay".
Revolutionary Features of NovoLISA
The NovoLISA platform incorporates two proprietary technologies: the LuxSit™ Pro luciferase reporter system and de novo binding protein reagents. This ingenious combination allows for a user-friendly assay experience, making it an exciting addition to any laboratory's toolkit. The platform boasts several key advantages: results in 15 minutes or less, a straightforward one-step no-wash protocol, no requirement for sample preparation, and compatibility with standard laboratory luminescence plate readers. According to Alfredo-Quijano Rubio, Ph.D., Chief Scientific Officer and co-founder of Monod Bio, "NovoLISA introduces a new generation of assays. Our AI-enhanced platform creates highly stable sensors with exceptional affinity and sensitivity for target analytes."
Product Launch of CRP Assay
The first product being launched on the NovoLISA platform is a C-Reactive Protein (CRP) assay. This assay is designed to measure levels of CRP, an important biomarker for inflammation. The components of the CRP NovoLISA include Split LuxSit™ CRP Biosensor proteins, the LuxSit™ Substrate, assay buffer, and a CRP analyte. When samples containing CRP are added, the luminescence signal increases in a dose-dependent manner, with minimal background interference in instances where CRP is absent. Daniel-Adriano Silva, Ph.D., CEO and co-founder of Monod Bio, expressed enthusiasm for the product launch, stating, "Introducing our second commercial product, which seamlessly integrates two of our innovative technologies, is a significant milestone for us."
Future of the NovoLISA Platform
The NovoLISA platform not only marks the launch of the CRP assay but also sets the stage for future developments. Monod Bio has plans to expand its offerings on this platform rapidly. Upcoming biosensors are anticipated to include assays for Human Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNFalpha), Human Interleukin-2 (IL-2), and Cardiac Troponin I (cTnI). This proactive approach demonstrates the company's commitment to rapid innovation and delivering advanced diagnostic solutions.
Understanding C-Reactive Protein
C-Reactive Protein (CRP), produced by the liver in response to inflammatory signals, plays a crucial role in identifying and addressing inflammation in the body. Elevated CRP levels can indicate various conditions, including infections and tissue damage. Monod Bio's Human C-Reactive Protein immunoassay is designed for quick quantification of CRP from different sample types, including cell culture supernatants, plasma, and serum, all in under 15 minutes without the need for wash steps.
About Monod Bio
Monod Bio emerged as a spinout from the Institute for Protein Design at UW Medicine, focusing on developing advanced protein-based solutions for research and in vitro diagnostics. Their innovative biosensor platform leverages state-of-the-art computational de novo protein design, allowing for swift and sensitive analytical assays. The company prides itself on being the first to commercialize a product based entirely on de novo proteins, with its research findings published in notable scientific journals.
Frequently Asked Questions
What is the NovoLISA platform?
The NovoLISA platform is a rapid biosensor assay system developed by Monod Bio designed to deliver quick and accurate results for research use.
How does the CRP assay work?
The CRP assay works by measuring luminescence levels in samples containing CRP, allowing for rapid and accurate detection in under 15 minutes.
What are the key features of the NovoLISA platform?
Key features include fast results, a simple no-wash protocol, no sample preparation needed, and compatibility with standard laboratory equipment.
How is CRP important in diagnostics?
CRP is a vital biomarker for inflammation and is used in clinical diagnostics to monitor and detect various inflammatory conditions.
What future products can we expect from Monod Bio?
Monod Bio plans to expand the NovoLISA platform with additional assays for various biomarkers, shortening the time for more advanced diagnostics.
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